Paul Komenda1, Nancy Yu2, Stella Leung2, Keevin Bernstein3, James Blanchard4, Manish Sood5, Claudio Rigatto1, Navdeep Tangri6. 1. Section of Nephrology, Department of Medicine, University of Manitoba, Winnipeg, Man. ; Seven Oaks General Hospital, Winnipeg, Man. 2. Department of Community Health Sciences, University of Manitoba, Winnipeg, Man. 3. Section of Nephrology, Department of Medicine, University of Manitoba, Winnipeg, Man. ; Health Sciences Centre, Winnipeg, Man. 4. Seven Oaks General Hospital, Winnipeg, Man. 5. Section of Nephrology, Department of Medicine, University of Manitoba, Winnipeg, Man. ; Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ont. 6. Section of Nephrology, Department of Medicine, University of Manitoba, Winnipeg, Man. ; Seven Oaks General Hospital, Winnipeg, Man. ; Department of Community Health Sciences, University of Manitoba, Winnipeg, Man.
Abstract
BACKGROUND: End-stage renal disease (ESRD) requiring dialysis is expensive and is associated with disproportionately poor health outcomes and quality of life. Understanding regional long-term secular trends in the incidence and prevalence of dialysis will allow for the alignment of appropriate and efficient delivery of care. The primary objective of this study was to describe long-term secular and geographic trends in ESRD over a 22-year period in a single-provider Canadian health care setting. METHODS: Using a previously validated case definition, we described the annual incidence and prevalence of ESRD in Manitoba from 1989 to 2010, stratified by age, sex and geographic location within the province. RESULTS: We searched more than 1.2 million records within the Manitoba Health repository. We identified 9489 patients in the Manitoba Health Physician Claims database with at least 1 claim for dialysis from 1989 through Mar. 31, 2010. Using the case definition of any 2 dialysis treatment claims, the total annual incidence of ESRD increased 2.5-fold from 15.8 to 40.2 per 100 000 during the study period. Of note, the northern rural portions of the province saw a 12-fold unadjusted increase in ESRD, from 8.1 per 100 000 in 1989 to 96.3 per 100 000 in 2009. INTERPRETATION: The incidence and prevalence of ESRD is increasing in Manitoba, most notably in the north of the province. Innovative interventions, such as primary screening and treatment initiatives, should specially target northern rural regions.
BACKGROUND:End-stage renal disease (ESRD) requiring dialysis is expensive and is associated with disproportionately poor health outcomes and quality of life. Understanding regional long-term secular trends in the incidence and prevalence of dialysis will allow for the alignment of appropriate and efficient delivery of care. The primary objective of this study was to describe long-term secular and geographic trends in ESRD over a 22-year period in a single-provider Canadian health care setting. METHODS: Using a previously validated case definition, we described the annual incidence and prevalence of ESRD in Manitoba from 1989 to 2010, stratified by age, sex and geographic location within the province. RESULTS: We searched more than 1.2 million records within the Manitoba Health repository. We identified 9489 patients in the Manitoba Health Physician Claims database with at least 1 claim for dialysis from 1989 through Mar. 31, 2010. Using the case definition of any 2 dialysis treatment claims, the total annual incidence of ESRD increased 2.5-fold from 15.8 to 40.2 per 100 000 during the study period. Of note, the northern rural portions of the province saw a 12-fold unadjusted increase in ESRD, from 8.1 per 100 000 in 1989 to 96.3 per 100 000 in 2009. INTERPRETATION: The incidence and prevalence of ESRD is increasing in Manitoba, most notably in the north of the province. Innovative interventions, such as primary screening and treatment initiatives, should specially target northern rural regions.
Authors: Elizabeth Thomlinson; Meg Kathleen McDonagh; Kathryn Baird Crooks; Margaret Lees Journal: Aust J Rural Health Date: 2004-12 Impact factor: 1.662
Authors: A S Levey; R Atkins; J Coresh; E P Cohen; A J Collins; K-U Eckardt; M E Nahas; B L Jaber; M Jadoul; A Levin; N R Powe; J Rossert; D C Wheeler; N Lameire; G Eknoyan Journal: Kidney Int Date: 2007-06-13 Impact factor: 10.612
Authors: Tone Britt Hortemo Osthus; Nanna von der Lippe; Lis Ribu; Tone Rustøen; Torbjørn Leivestad; Toril Dammen; Ingrid Os Journal: BMC Nephrol Date: 2012-08-03 Impact factor: 2.388
Authors: Reid H Whitlock; Mariette Chartier; Paul Komenda; Jay Hingwala; Claudio Rigatto; Randy Walld; Allison Dart; Navdeep Tangri Journal: Can J Kidney Health Dis Date: 2017-04-20