| Literature DB >> 25843358 |
Weijun Fu1, Mei Zhu1, Guanglong Zou2, Chen Xu1, Zhiqiang Wang1, Baoming Ji1.
Abstract
A mild and efficient method for the synthesis of 3-difluoroacetylated coumarins through visible-light-promoted aryldifluoroacetylation of alkynes with ethyl bromodifluoroacetate has been developed. The reaction allows the direct formation of Csp(2)-CF2COOEt and C-C bonds via a proposed tandem radical cyclization process.Entities:
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Year: 2015 PMID: 25843358 DOI: 10.1021/acs.joc.5b00305
Source DB: PubMed Journal: J Org Chem ISSN: 0022-3263 Impact factor: 4.354