| Literature DB >> 25842969 |
Frank Soldner1, Rudolf Jaenisch2.
Abstract
Understanding how genetic risk variants contribute to complex diseases is crucial for predicting disease susceptibility and developing patient-tailored therapies. In this issue of Cell Stem Cell, Young et al. (2015) dissect the function of common non-coding risk haplotypes in the SORL1 locus in the pathogenesis of sporadic Alzheimer's disease using patient-derived induced pluripotent stem cells.Entities:
Mesh：
Substances：
Year: 2015 PMID： 25842969 DOI： 10.1016/j.stem.2015.03.010
Source DB: PubMed Journal: Cell Stem Cell ISSN： 1875-9777 Impact factor: 24.633