Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 5-HT3 receptor antagonists for the treatment of nausea/vomiting.

Literature DB >> 25841471

5-HT3 receptor antagonists for the treatment of nausea/vomiting.

Howard S Smith¹, Lorraine R Cox², Eric J Smith³.

Abstract

It is well appreciated that a number of things (e.g., various insults, chemotherapeutic agents, radiation) may lead to the release of serotonin from the enterochromaffin of the gastrointestinal tract. Released serotonin may then bind to certain 5-HT3 receptors and promote nausea/vomiting. 5-HT3 receptor antagonists may ameliorate nausea/vomiting in a number of circumstances and have been utilized as important antiemetics for multiple conditions such as chemotherapy-induced nausea/vomiting (CINV), radiation-induced emesis (RIS), and postoperative nausea/vomiting (PONV).

Entities: Chemical Disease

Keywords: 5-HT3 antagonists; Nausea/Vomiting; chemotherapy-induced nausea/vomiting; ondansetron; palonostron; postoperative nausea/vomiting; serotonin

Year: 2012 PMID： 25841471 DOI： 10.3978/j.issn.2224-5820.2012.07.07

Source DB: PubMed Journal: Ann Palliat Med ISSN： 2224-5820

Keyword Cloud
Cited

16 in total

1. Comparison of ondansetron and granisetron for antiemetic prophylaxis in maxillofacial surgery patients receiving general anesthesia: a prospective, randomised, and double blind study.

Authors: Kiran Savant; Rakshit Vijay Sinai Khandeparker; Vikas Berwal; Purva Vijay Khandeparker; Hunny Jain
Journal: J Korean Assoc Oral Maxillofac Surg Date: 2016-04-27

2. Palonosetron and hydroxyzine pre-treatment reduces the objective signs of experimentally-induced acute opioid withdrawal in humans: a double-blinded, randomized, placebo-controlled crossover study.

Authors: Matthew J Erlendson; Nicole D'Arcy; Ellen M Encisco; Jeffrey J Yu; Lorena Rincon-Cruz; Gary Peltz; J David Clark; Larry F Chu
Journal: Am J Drug Alcohol Abuse Date: 2016-08-11 Impact factor: 3.829

3. Male and female rats exhibit comparable gaping behavior but activate brain regions differently during expression of conditioned nausea.

Authors: Alyssa Bernanke; Samantha Sette; Nathaniel Hernandez; Sara Zimmerman; Justine Murphy; Reynold Francis; Zackery Reavis; Cynthia Kuhn
Journal: Behav Pharmacol Date: 2022-05-10 Impact factor: 2.277

Review 4. The Impact of 5-HT3RA Use on Cost and Utilization in Patients with Chemotherapy-Induced Nausea and Vomiting: Systematic Review of the Literature.

Authors: Michael S Broder; Claudio Faria; Annette Powers; Jehangeer Sunderji; Dasha Cherepanov
Journal: Am Health Drug Benefits Date: 2014-05

5. The 5-HT₃ Receptor Affects Rotavirus-Induced Motility.

Authors: Marie Hagbom; Arash Hellysaz; Claudia Istrate; Johan Nordgren; Sumit Sharma; Felipe Meira de-Faria; Karl-Eric Magnusson; Lennart Svensson
Journal: J Virol Date: 2021-07-12 Impact factor: 5.103

Review 6. Internal senses of the vagus nerve.

Authors: Sara L Prescott; Stephen D Liberles
Journal: Neuron Date: 2022-01-19 Impact factor: 17.173

5-HT3 receptor antagonists for the treatment of nausea/vomiting.

1. Comparison of ondansetron and granisetron for antiemetic prophylaxis in maxillofacial surgery patients receiving general anesthesia: a prospective, randomised, and double blind study.

2. Palonosetron and hydroxyzine pre-treatment reduces the objective signs of experimentally-induced acute opioid withdrawal in humans: a double-blinded, randomized, placebo-controlled crossover study.

3. Male and female rats exhibit comparable gaping behavior but activate brain regions differently during expression of conditioned nausea.

Review 4. The Impact of 5-HT3RA Use on Cost and Utilization in Patients with Chemotherapy-Induced Nausea and Vomiting: Systematic Review of the Literature.

5. The 5-HT₃ Receptor Affects Rotavirus-Induced Motility.

Review 6. Internal senses of the vagus nerve.

Review 7. Cancer in pregnancy: disentangling treatment modalities.

8. Azologization of serotonin 5-HT₃ receptor antagonists.

9. In Vitro Inhibition of Renal OCT2 and MATE1 Secretion by Antiemetic Drugs.

Review 10. Recent advances in antiemetics: new formulations of 5HT₃-receptor antagonists.

5-HT3 receptor antagonists for the treatment of nausea/vomiting.

1. Comparison of ondansetron and granisetron for antiemetic prophylaxis in maxillofacial surgery patients receiving general anesthesia: a prospective, randomised, and double blind study.

2. Palonosetron and hydroxyzine pre-treatment reduces the objective signs of experimentally-induced acute opioid withdrawal in humans: a double-blinded, randomized, placebo-controlled crossover study.

3. Male and female rats exhibit comparable gaping behavior but activate brain regions differently during expression of conditioned nausea.

Review 4. The Impact of 5-HT3RA Use on Cost and Utilization in Patients with Chemotherapy-Induced Nausea and Vomiting: Systematic Review of the Literature.

5. The 5-HT3 Receptor Affects Rotavirus-Induced Motility.

Review 6. Internal senses of the vagus nerve.

Review 7. Cancer in pregnancy: disentangling treatment modalities.

8. Azologization of serotonin 5-HT3 receptor antagonists.

9. In Vitro Inhibition of Renal OCT2 and MATE1 Secretion by Antiemetic Drugs.

Review 10. Recent advances in antiemetics: new formulations of 5HT3-receptor antagonists.

5. The 5-HT₃ Receptor Affects Rotavirus-Induced Motility.

8. Azologization of serotonin 5-HT₃ receptor antagonists.

Review 10. Recent advances in antiemetics: new formulations of 5HT₃-receptor antagonists.