Rafel Tappouni1, Paul Mathew2, Tara M Connelly2, Franklyn Luke3, Evangelos Messaris4. 1. Department of radiology, Wake Forest School of Medicine, One Medical Center Boulevard, Winston-Salem, NC 27157, USA. 2. Department of Surgery, Division of Colon & Rectal Surgery, The Pennsylvania State University, College of Medicine, 500 University Drive, Hershey, PA 17033, USA. 3. Department of radiology, The Pennsylvania State University, College of Medicine, 500 University Drive, Hershey, PA 17033, USA. 4. Department of Surgery, Division of Colon & Rectal Surgery, The Pennsylvania State University, College of Medicine, 500 University Drive, Hershey, PA 17033, USA. Electronic address: emessaris@hmc.psu.edu.
Abstract
BACKGROUND: Visceral and subcutaneous abdominal fat parameters have been associated with worse surgical outcomes in colorectal cancer but have not been investigated in diverticulitis. METHODS: Volumetric fat parameters were measured on preoperative computed tomography scans from 211 diverticulitis patients. Primary outcome was a serious postoperative complication (Clavien-Dindo grades 2-4). Variables including age, disease duration, American Society of Anesthesiology score, ostomy, immunosuppression, body mass index, and volumetric fat parameters were examined. SPSS was used for statistics. RESULTS: The serious postoperative complication rate was 12.7%. On univariate analysis, several factors including older age (P = .0001), ostomy creation (P = .02), higher visceral fat (VF, P = .01), emergent surgery (P = .05), and higher American Society of Anesthesiology score (P = .05) were associated with complications. On multivariate regression analysis, only VF was independently associated with complications. CONCLUSIONS: Diverticulitis patients with high VF are more likely to develop complications after sigmoidectomy. VF measurement may potentially be used as a tool to assist in surgical decision making and prediction of outcomes.
BACKGROUND: Visceral and subcutaneous abdominal fat parameters have been associated with worse surgical outcomes in colorectal cancer but have not been investigated in diverticulitis. METHODS: Volumetric fat parameters were measured on preoperative computed tomography scans from 211 diverticulitispatients. Primary outcome was a serious postoperative complication (Clavien-Dindo grades 2-4). Variables including age, disease duration, American Society of Anesthesiology score, ostomy, immunosuppression, body mass index, and volumetric fat parameters were examined. SPSS was used for statistics. RESULTS: The serious postoperative complication rate was 12.7%. On univariate analysis, several factors including older age (P = .0001), ostomy creation (P = .02), higher visceral fat (VF, P = .01), emergent surgery (P = .05), and higher American Society of Anesthesiology score (P = .05) were associated with complications. On multivariate regression analysis, only VF was independently associated with complications. CONCLUSIONS:Diverticulitispatients with high VF are more likely to develop complications after sigmoidectomy. VF measurement may potentially be used as a tool to assist in surgical decision making and prediction of outcomes.
Authors: Benjamin A Kuritzkes; Emmanouil P Pappou; Ravi P Kiran; Onur Baser; Liqiong Fan; Xiaotao Guo; Binsheng Zhao; Stuart Bentley-Hibbert Journal: Int J Colorectal Dis Date: 2018-04-15 Impact factor: 2.571
Authors: Peter K Twining; Olivier Q Groot; Colleen G Buckless; Neal D Kapoor; Michiel E R Bongers; Stein J Janssen; Joseph H Schwab; Martin Torriani; Miriam A Bredella Journal: J Am Acad Orthop Surg Glob Res Rev Date: 2022-03-09