Fabrício Kitazono de Carvalho1, Alexandra Mussolino de Queiroz2, Raquel Assed Bezerra da Silva2, Regina Sawamura3, Luciano Bachmann4, Léa Assed Bezerra da Silva5, Paulo Nelson-Filho5. 1. Professor, Department of Pediatric Dentistry, University of São Paulo - School of Dentistry of Ribeirão Preto, Ribeirão Preto, São Paulo, Brazil. Electronic address: Fabricio@hotmail.com. 2. Professor, Department of Pediatric Dentistry, University of São Paulo - School of Dentistry of Ribeirão Preto, Ribeirão Preto, São Paulo, Brazil. 3. Professor, Department of Childcare and Pediatrics, University of São Paulo - School of Medicine of Ribeirão Preto, Ribeirão Preto, São Paulo, Brazil. 4. Professor, Department of Physics, University of São Paulo - School of Philosophy, Sciences and Letters of Ribeirão Preto, Ribeirão Preto, São Paulo, Brazil. 5. Full Professor, Department of Pediatric Dentistry, University of São Paulo - School of Dentistry of Ribeirão Preto, Ribeirão Preto, São Paulo, Brazil.
Abstract
OBJECTIVE: The aim of this study was to evaluate the oral manifestations of celiac disease (CD), the chemical composition of dental enamel, and the occurrence of CD in children with dental enamel defects (DEDs). STUDY DESIGN: In the study, 52 children with CD and 52 controls were examined for DEDs, recurrent aphthous stomatitis (RAS), dental caries experience, and salivary parameters. In addition, 10 exfoliated primary enamel molars from each group were analyzed by energy dispersive x-ray spectroscopy and Fourier transform infrared spectroscopy. Fifty children with DEDs were submitted to CD diagnosis. RESULTS: Among the children with CD, a higher prevalence of DEDs (P = .00001) and RAS (P = .0052), lower caries experience (P = .0024), and reduction of salivary flow (P = .0060) were observed. Dental enamel from the children with CD demonstrated a lower calcium-to-phosphorus ratio (P = .0136), but no difference in the carbonate-to-phosphate ratio (P = .5862) was observed. In the multivariate analysis, CD was a protective factor for caries (OR = 0.74) and a risk factor for RAS (OR3.23). CONCLUSIONS: The children with CD presented with more RAS, DEDs, reduction of salivary flow, and chemical alterations in the enamel.
OBJECTIVE: The aim of this study was to evaluate the oral manifestations of celiac disease (CD), the chemical composition of dental enamel, and the occurrence of CD in children with dental enamel defects (DEDs). STUDY DESIGN: In the study, 52 children with CD and 52 controls were examined for DEDs, recurrent aphthous stomatitis (RAS), dental caries experience, and salivary parameters. In addition, 10 exfoliated primary enamel molars from each group were analyzed by energy dispersive x-ray spectroscopy and Fourier transform infrared spectroscopy. Fifty children with DEDs were submitted to CD diagnosis. RESULTS: Among the children with CD, a higher prevalence of DEDs (P = .00001) and RAS (P = .0052), lower caries experience (P = .0024), and reduction of salivary flow (P = .0060) were observed. Dental enamel from the children with CD demonstrated a lower calcium-to-phosphorus ratio (P = .0136), but no difference in the carbonate-to-phosphate ratio (P = .5862) was observed. In the multivariate analysis, CD was a protective factor for caries (OR = 0.74) and a risk factor for RAS (OR3.23). CONCLUSIONS: The children with CD presented with more RAS, DEDs, reduction of salivary flow, and chemical alterations in the enamel.
Authors: Viviana Marisa Pereira Macho; Ana Sofia Coelho; Diana Maria Veloso E Silva; David José Casimiro de Andrade Journal: Open Dent J Date: 2017-10-24
Authors: Farah A Alsadat; Najlaa M Alamoudi; Azza A El-Housseiny; Osama M Felemban; Faisal M Dardeer; Omar I Saadah Journal: BMC Oral Health Date: 2021-12-29 Impact factor: 2.757
Authors: Viviana Marisa Pereira Macho; Maria Conceição Antas de Barros Menéres Manso; Diana Maria Veloso E Silva; David José Casimiro de Andrade Journal: J Dent Sci Date: 2020-03-28 Impact factor: 2.080