Literature DB >> 25840073

Management of challenging congenital melanocytic nevi: outcomes study of serial excision.

Aladdin H Hassanein1, Gary F Rogers2, Arin K Greene3.   

Abstract

BACKGROUND: Large congenital melanocytic nevi (CMN) cause significant deformity and are at risk for malignant degeneration. Techniques used to remove difficult CMN include serial excision, skin grafting, or tissue expansion. Some authors prefer skin grafting or tissue expansion if several stages would be required to serially resect the CMN. The purpose of this study was to determine the efficacy of serial excision for CMN requiring ≥3 procedures.
METHODS: Medical records and clinical images of patients with CMN treated between 2007 and 2013 were reviewed. Inclusion criteria were: (1) lesions that required ≥3 serial excisions to remove and (2) CMN that could have been treated reasonably with skin grafting or tissue expansion. Patient age, gender, location of the lesion, size of the CMN, number of serial excisions, and complications were recorded.
RESULTS: The study included 21 patients. Lesions were located on the lower extremity (38.1%), head/neck (33.3%), upper extremity (14.3%), or trunk (14.3%). Nevus size was 2.2%±1.2% total body surface area. The age during the first operation was 4.3 years (range 3 months to 15 years). The number of excisions was 3.5±0.7, spaced 8.2±4.3 months apart. Partial suture line dehiscence occurred after 2/72 operations and seroma resulted after 1/72 operations; there were no infections.
CONCLUSION: Challenging CMN amenable to serial excision can be removed effectively and safely using this technique. Children are left with a favorable linear scar, do not have donor or recipient site morbidity from skin grafting, and are not subjected to potential tissue expander complications and injections required for expansion.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Congenital; Giant; Melanoma; Nevus; Skin graft; Tissue expander

Mesh:

Year:  2014        PMID: 25840073     DOI: 10.1016/j.jpedsurg.2014.08.020

Source DB:  PubMed          Journal:  J Pediatr Surg        ISSN: 0022-3468            Impact factor:   2.545


  4 in total

1.  Bayesian calibration of a computational model of tissue expansion based on a porcine animal model.

Authors:  Tianhong Han; Taeksang Lee; Joanna Ledwon; Elbert Vaca; Sergey Turin; Aaron Kearney; Arun K Gosain; Adrian B Tepole
Journal:  Acta Biomater       Date:  2021-10-08       Impact factor: 8.947

2.  Giant congenital melanocytic nevi: 40 years of experience with the serial excision technique.

Authors:  Lais de Abreu Mutti; Marta Regina Machado Mascarenhas; João Marcos Goes de Paiva; Ronaldo Golcman; Mauro Yoshiaki Enokihara; Benjamin Golcman
Journal:  An Bras Dermatol       Date:  2017 Mar-Apr       Impact factor: 1.896

3.  Skin Wound Tension Reduction Device Combined with Ablative Fractional Carbon Dioxide Laser to Reduce Scar Formation After Excision of Pediatric Facial Skin Lesions: A Prospective Cohort Study.

Authors:  Haiting Xu; Jing Li; Zifu Zhou; Jianhai Bi; Xiaoyang Li; Ran Huo
Journal:  Clin Cosmet Investig Dermatol       Date:  2022-02-22

4.  Serial Excision for Treatment of Non-melanoma Skin Cancer.

Authors:  Paige K Dekker; Mark D Mishu; Richard Youn; Stephen B Baker
Journal:  Plast Reconstr Surg Glob Open       Date:  2021-06-10
  4 in total

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