Fabrizio di Francesco1, Laura Del Prete2, Chiara Grimaldi3, Lidia Monti4, Jean de Ville de Goyet5. 1. Hepatobiliary Surgery Unit, Department of Surgery, Bambino Gesù Children's Hospital, Roma, Italy. Electronic address: fdifra@yahoo.it. 2. Pediatric Surgery, University of Roma Tor Vergata, Roma, Italy. 3. Hepatobiliary Surgery Unit, Department of Surgery, Bambino Gesù Children's Hospital, Roma, Italy. 4. Hepatobiliary Radiology Unit, Department of Imaging, Bambino Gesù Children's Hospital, Roma, Italy. 5. Hepatobiliary Surgery Unit, Department of Surgery, Bambino Gesù Children's Hospital, Roma, Italy; Pediatric Surgery, University of Roma Tor Vergata, Roma, Italy.
Abstract
BACKGROUND: The association of pancreatitis and portal vein thrombosis (PVT) is extremely rare in children. We report on 3 cases which suggest that there may be a causal relation between the two. METHODS: Clinical characteristics and evolution of 3 children with this particular condition were analyzed retrospectively. In this group of patients, the strategy consisted in opting for early surgical decompression of the portal hypertension, which was followed by a favorable outcome, not only in terms of complications related to the portal hypertension but also of a contemporaneous spontaneous regression of the concurrent pancreatic disease, in absence of any other specific management of the latter problem. RESULTS AND CONCLUSIONS: Combined PVT and pancreatitis is exceptional in children. Although this series is small, it provides insight and some evidence that the pancreatic disease might be secondary to the cavernomatous transformation of the regional venous system. More interestingly, it suggests that the appropriate management strategy should be to rapidly relieve portal hypertension after resolution of the acute phase of pancreatitis.
BACKGROUND: The association of pancreatitis and portal vein thrombosis (PVT) is extremely rare in children. We report on 3 cases which suggest that there may be a causal relation between the two. METHODS: Clinical characteristics and evolution of 3 children with this particular condition were analyzed retrospectively. In this group of patients, the strategy consisted in opting for early surgical decompression of the portal hypertension, which was followed by a favorable outcome, not only in terms of complications related to the portal hypertension but also of a contemporaneous spontaneous regression of the concurrent pancreatic disease, in absence of any other specific management of the latter problem. RESULTS AND CONCLUSIONS: Combined PVT and pancreatitis is exceptional in children. Although this series is small, it provides insight and some evidence that the pancreatic disease might be secondary to the cavernomatous transformation of the regional venous system. More interestingly, it suggests that the appropriate management strategy should be to rapidly relieve portal hypertension after resolution of the acute phase of pancreatitis.
Authors: Mauricio Figueroa-Sánchez; Carlos M Nuño-Guzmán; M Carmen Álvarez-López; Mariana Ordónez-Cárdenas; Leidy J Montaño-Rodríguez Journal: Front Surg Date: 2022-04-01
Authors: Chinenye R Dike; Gretchen Cress; Douglas S Fishman; Tanja Gonska; Chee Y Ooi; Emily R Perito; David Troendle; Cynthia M Tsai; Mark E Lowe; Aliye Uc Journal: J Pediatr Gastroenterol Nutr Date: 2021-10-01 Impact factor: 3.288