Gianni Pedrizzetti1, Partho P Sengupta2. 1. Department of Engineering and Architecture, University of Trieste, Trieste, Italy. 2. Zena and Michael A. Wiener Cardiovascular Institute, School of Medicine at Mount Sinai, One Gustave L. Levy Place, PO Box 1030, New York, NY 10029, USA sengupta.partho@mountsinai.org.