Literature DB >> 25839430

γHV68 vGAT: a viral pseudoenzyme pimping for PAMPs.

Daniel Kolakofsky1, Dominique Garcin2.   

Abstract

In this issue, He et al. (2015) show how herpes virus usurps a cellular metabolic enzyme to induce RIG-I deamidation and RNA-independent activation, likely to better prevent further innate immune responses.
Copyright © 2015 Elsevier Inc. All rights reserved.

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Year:  2015        PMID: 25839430     DOI: 10.1016/j.molcel.2015.03.021

Source DB:  PubMed          Journal:  Mol Cell        ISSN: 1097-2765            Impact factor:   17.970


  1 in total

1.  A Viral Deamidase Targets the Helicase Domain of RIG-I to Block RNA-Induced Activation.

Authors:  Jun Zhao; Yi Zeng; Simin Xu; Jie Chen; Guobo Shen; Caiqun Yu; David Knipe; Weiming Yuan; Jian Peng; Wenqing Xu; Chao Zhang; Zanxian Xia; Pinghui Feng
Journal:  Cell Host Microbe       Date:  2016-11-17       Impact factor: 21.023

  1 in total

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