| Literature DB >> 25836945 |
Hajime Maeda1, Akira Kubota2, Akira Kanamori2, Yasushi Tanaka3, Yasuo Terauchi4, Ikuro Matsuba2.
Abstract
We found a slight elevation of serum creatinine in the subjects treated with sitagliptin for 2 years and a correlation between creatinine elevation and HbA1c reduction. These results suggest that creatinine elevation is associated with activation of incretin, most possibly with up-regulation of diuretic activity of GLP-1.Entities:
Keywords: Creatinine; Dipeptidyl peptidase-4 (DPP-4) inhibitor; HbA1c; Sitagliptin
Mesh:
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Year: 2015 PMID: 25836945 DOI: 10.1016/j.diabres.2015.03.008
Source DB: PubMed Journal: Diabetes Res Clin Pract ISSN: 0168-8227 Impact factor: 5.602