Literature DB >> 25835626

Predictors of radiation therapy noncompliance in an urban academic cancer center.

Nitin Ohri1, Bruce D Rapkin2, Debayan Guha1, Hilda Haynes-Lewis1, Chandan Guha1, Shalom Kalnicki1, Madhur Garg3.   

Abstract

PURPOSE: To quantify the frequency of patient noncompliance in an urban radiation oncology department and identify predictors of noncompliance. METHODS AND MATERIALS: We identified patients treated with external beam radiation therapy (RT) with curative intent in our department from 2007 to 2012 for 1 of 7 commonly treated malignancies. Patients who missed 2 or more scheduled RT appointments were deemed "noncompliant." An institutional database was referenced to obtain clinical and demographic information for each patient, as well as a quantitative estimate of each patient's socioeconomic status. Logistic regression was used to identify factors associated with RT noncompliance.
RESULTS: A total of 2184 patients met eligibility criteria. Of these, 442 (20.2%) were deemed "noncompliant." On multivariate analysis, statistically significant predictors of noncompliance included diagnosis of head-and-neck, cervical, or uterine cancer, treatment during winter months, low socioeconomic status, and use of a long treatment course (all P<.05).
CONCLUSION: This is the first large effort examining patient noncompliance with daily RT. We have identified demographic, clinical, and treatment-related factors that can be used to identify patients at high risk for noncompliance. These findings may inform future strategies to improve adherence to prescribed therapy.
Copyright © 2015 Elsevier Inc. All rights reserved.

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Year:  2015        PMID: 25835626     DOI: 10.1016/j.ijrobp.2014.09.030

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN: 0360-3016            Impact factor:   7.038


  13 in total

1.  The "rocky treatment course": identifying a high-risk subgroup of head and neck cancer patients for supportive interventions.

Authors:  Horia Vulpe; Janet Ellis; Shao Hui Huang; Eshetu G Atenafu; Raymond W Jang; Gary Rodin; Jolie Ringash
Journal:  Support Care Cancer       Date:  2016-11-04       Impact factor: 3.603

2.  Refusal of Local Therapy in Esophageal Cancer and Impact on Overall Survival.

Authors:  Matthew Parsons; Shane Lloyd; Skyler Johnson; Courtney Scaife; Thomas Varghese; Robert Glasgow; Ignacio Garrido-Laguna; Randa Tao
Journal:  Ann Surg Oncol       Date:  2020-07-09       Impact factor: 5.344

3.  Association Between Incomplete Neoadjuvant Radiotherapy and Survival for Patients With Locally Advanced Rectal Cancer.

Authors:  Kyle Freischlag; Zhifei Sun; Mohamed A Adam; Jina Kim; Manisha Palta; Brian G Czito; John Migaly; Christopher R Mantyh
Journal:  JAMA Surg       Date:  2017-06-01       Impact factor: 14.766

Review 4.  Appraisal assessment in patient-reported outcome research: methods for uncovering the personal context and meaning of quality of life.

Authors:  Carolyn E Schwartz; Joel A Finkelstein; Bruce D Rapkin
Journal:  Qual Life Res       Date:  2016-12-17       Impact factor: 4.147

Review 5.  Big Data From Small Devices: The Future of Smartphones in Oncology.

Authors:  Juhi M Purswani; Adam P Dicker; Colin E Champ; Matt Cantor; Nitin Ohri
Journal:  Semin Radiat Oncol       Date:  2019-10       Impact factor: 5.934

6.  Better compliance with hypofractionation vs. conventional fractionation in adjuvant breast cancer radiotherapy : Results of a single, institutional, retrospective study.

Authors:  Volker Rudat; Alaa Nour; Mohamed Hammoud; Salam Abou Ghaida
Journal:  Strahlenther Onkol       Date:  2017-02-23       Impact factor: 3.621

7.  A randomized controlled trial comparing concurrent chemoradiation versus concurrent chemoradiation followed by adjuvant chemotherapy in locally advanced cervical cancer patients: ACTLACC trial.

Authors:  Siriwan Tangjitgamol; Ekkasit Tharavichitkul; Chokaew Tovanabutra; Kanisa Rongsriyam; Tussawan Asakij; Kannika Paengchit; Jirasak Sukhaboon; Somkit Penpattanagul; Apiradee Kridakara; Jitti Hanprasertpong; Kittisak Chomprasert; Sirentra Wanglikitkoon; Thiti Atjimakul; Piyawan Pariyawateekul; Kanyarat Katanyoo; Prapai Tanprasert; Wanwipa Janweerachai; Duangjai Sangthawan; Jakkapan Khunnarong; Taywin Chottetanaprasith; Busaba Supawattanabodee; Prasert Lertsanguansinchai; Jatupol Srisomboon; Wanrudee Isaranuwatchai; Vichan Lorvidhaya
Journal:  J Gynecol Oncol       Date:  2019-04-10       Impact factor: 4.401

8.  Survival impact of prolonged postoperative radiation therapy for patients with glioblastoma treated with combined-modality therapy.

Authors:  Mehran B Yusuf; Jeremy Gaskins; Mark J Amsbaugh; Shiao Woo; Eric Burton
Journal:  Neurooncol Pract       Date:  2018-07-20

9.  Feasibility of concomitant cisplatin with hypofractionated radiotherapy for locally advanced head and neck squamous cell carcinoma.

Authors:  Alexandre Arthur Jacinto; Eronides Salustiano Batalha Filho; Luciano de Souza Viana; Pedro De Marchi; Renato de Castro Capuzzo; Ricardo Ribeiro Gama; Domingos Boldrini Junior; Carlos Roberto Santos; Gustavo Dix Junqueira Pinto; Josiane Mourão Dias; Heloisa Pelisser Canton; Raiany Carvalho; Lucas Augusto Radicchi; Soren Bentzen; Eduardo Zubizarreta; Andre Lopes Carvalho
Journal:  BMC Cancer       Date:  2018-10-23       Impact factor: 4.430

10.  Overcoming Barriers to Radiation Oncology Access in Low-Resource Settings in the United States.

Authors:  Malcolm D Mattes; Gita Suneja; Bruce G Haffty; Cristiane Takita; Matthew S Katz; Nitin Ohri; Curtiland Deville; Malika L Siker; Henry S Park
Journal:  Adv Radiat Oncol       Date:  2021-09-10
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