Literature DB >> 25834926

Antioxidant and antitumor activities in vitro of polysaccharides from E. sipunculoides.

Rongjun He1, Yuejun Zhao1, Ruina Zhao1, Peilong Sun2.   

Abstract

Three polysaccharides (SAP30, SAP60 and SAP80) were separated from the body of Edwardsia sipunculoides by tissue homogenate and papain hydrolysis. Total soluble sugar contents, monosaccharide compositions, antioxidant and antitumor activities in vitro of those polysaccharides were investigated, respectively. Results showed that the total soluble sugar contents of SAP composed of Man, GlcN, Rha, GalN, GlcUA, Glc, Gal, Xyl and Fuc were more than 85% estimated by the phenol-sulfuric acid assay. In addition, SAP had potential antioxidant and antitumor activities. SAP30 has the most significant antitumor effect. This study suggested that SAP could be a potential natural antioxidants and antitumor agents.
Copyright © 2015 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Antioxidant; Antitumor; E. sipunculoides; Polysaccharide

Mesh：

Substances：

Year:  2015        PMID： 25834926     DOI： 10.1016/j.ijbiomac.2015.03.030

Source DB:  PubMed          Journal:  Int J Biol Macromol        ISSN： 0141-8130            Impact factor:   6.953


  7 in total

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  7 in total

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