BACKGROUND: Crimean-Congo hemorrhagic fever (CCHF) is an endemic disease in Turkey. The clinical presentation and laboratory findings are not specific especially in cases without hemorrhagic findings. OBJECTIVE: We aimed to evaluate CCHF cases and compare them with non-CCHF cases in terms of their characteristics during admission. METHODS: Cases with a preliminary diagnosis of CCHF at a secondary care hospital in Kastamonu in 2013 were evaluated, retrospectively. Cases testing RNA/IgM positive were considered as CCHF. Cases testing both RNA and IgM negative were considered as non-CCHF. The two groups were then compared in terms of their clinical, laboratory and epidemiological characteristics during admission. RESULTS: A total of 41 cases were tested and CCHF was found in 46.3% of cases. Fatality was 5.3% in CCHF cases. The frequency of tick bites and CK elevation in CCHF cases was significantly higher than non-CCHF cases (p<0.05). There were no significant differences between the two groups regarding other characteristics (p>0.05). CONCLUSIONS: In cases with a preliminary diagnosis of CCHF, especially in cases without a history of tick bite and with normal CK levels during admission, performing tests for the differential diagnosis may be advisable without waiting for the results of tests for CCHF.
BACKGROUND:Crimean-Congo hemorrhagic fever (CCHF) is an endemic disease in Turkey. The clinical presentation and laboratory findings are not specific especially in cases without hemorrhagic findings. OBJECTIVE: We aimed to evaluate CCHF cases and compare them with non-CCHF cases in terms of their characteristics during admission. METHODS: Cases with a preliminary diagnosis of CCHF at a secondary care hospital in Kastamonu in 2013 were evaluated, retrospectively. Cases testing RNA/IgM positive were considered as CCHF. Cases testing both RNA and IgM negative were considered as non-CCHF. The two groups were then compared in terms of their clinical, laboratory and epidemiological characteristics during admission. RESULTS: A total of 41 cases were tested and CCHF was found in 46.3% of cases. Fatality was 5.3% in CCHF cases. The frequency of tick bites and CK elevation in CCHF cases was significantly higher than non-CCHF cases (p<0.05). There were no significant differences between the two groups regarding other characteristics (p>0.05). CONCLUSIONS: In cases with a preliminary diagnosis of CCHF, especially in cases without a history of tick bite and with normal CK levels during admission, performing tests for the differential diagnosis may be advisable without waiting for the results of tests for CCHF.
Authors: Ali Kemal Erenler; Fuat Kulaksiz; Hüseyin Ülger; Murat Erdem; Cem Koçak; Fatih Söylemez; Özkan Öztürk; Ahmet Baydin Journal: Trop Doct Date: 2014-01-15 Impact factor: 0.731
Authors: Dennis A Bente; Naomi L Forrester; Douglas M Watts; Alexander J McAuley; Chris A Whitehouse; Mike Bray Journal: Antiviral Res Date: 2013-07-29 Impact factor: 5.970