| Literature DB >> 25833883 |
Laurent Pison1, Tatjana S Potpara2, Jian Chen3, Torben B Larsen4, Maria Grazia Bongiorni5, Carina Blomström-Lundqvist.
Abstract
The purpose of this EP Wire was to assess the indications, techniques, and outcomes of left atrial appendage occlusion (LAAO) in Europe. Thirty-three European centres, all members of the European Heart Rhythm Association electrophysiology (EP) research network, responded to this survey by completing the questionnaire. The major indication for LAAO (94%) was the prevention of stroke in patients at high thrombo-embolic risk (CHA2DS2-VASc ≥ 2) and contraindications to oral anticoagulants (OACs). Twenty-one (64%) of the responding centres perform LAAO in their own institution and 80% implanted 30 or less LAAO devices in 2014. Two-dimensional transoesophageal echocardiography was the preferred imaging technique to visualize LAA before, during, and after LAAO in 79, 58, and 62% of the participating centres, respectively. Following LAAO, 49% of the centres prescribe vitamin K antagonists or novel OACs. Twenty-five per cent of the centres combine LAAO with pulmonary vein isolation. The periprocedural complications included death (range, 0-3%), ischaemic or haemorrhagic stroke (0-25%), tamponade (0-25%), and device embolization (0-20%). In conclusion, this EP Wire has demonstrated that LAAO is most commonly employed in patients at high thrombo-embolic risk in whom OAC is contraindicated. The technique is not yet very widespread and the complication rates remain significant. Published on behalf of the European Society of Cardiology. All rights reserved.Entities:
Keywords: Anticoagulation; Atrial fibrillation; EHRA survey; EP wire; Left atrial appendage; Occluder; Outcome; Stroke
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Year: 2015 PMID: 25833883 DOI: 10.1093/europace/euv069
Source DB: PubMed Journal: Europace ISSN: 1099-5129 Impact factor: 5.214