| Literature DB >> 2583358 |
K S Cheah1, A M Cheah, J E Fletcher, H Rosenberg.
Abstract
1. Skeletal muscle mitochondria of malignant hyperthermia (MH)-susceptible patients showed normal oxidative phosphorylation but were more easily uncoupled than normal by exogenous Ca2+. 2. Fatty acids, in stimulating the mitochondrial ATPase activity, are responsible for the enhanced State 4 respiration in MH-susceptible patients. 3. These results imply that skeletal muscle mitochondria and free fatty acids are associated with the development of MH syndrome.Entities:
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Year: 1989 PMID： 2583358 DOI： 10.1016/0020-711x(89)90291-7
Source DB: PubMed Journal: Int J Biochem ISSN： 0020-711X