Deveshni Reddy1, Brenda M Morrow2, Andrew C Argent1. 1. Paediatric Intensive Care Unit, Red Cross War Memorial Children's Hospital, Rondebosch, Cape Town, 7700, South Africa Department of Paediatrics and Child Health, University of Cape Town, Cape Town, 7700, South Africa. 2. Department of Paediatrics and Child Health, University of Cape Town, Cape Town, 7700, South Africa brenda.morrow@uct.ac.za.
Abstract
OBJECTIVES: To describe and compare characteristics and outcomes of patients colonized or infected with Acinetobacter baumannii (cases) to a control group. METHODS: A retrospective case-controlled study of patients admitted to a South African paediatric intensive care unit (PICU) between January and December 2010. RESULTS: Acinetobacter baumannii was isolated in 194 patients. Mortality was similar between cases (9.3%) and controls (9.8%). Median duration of PICU stay and mechanical ventilation in cases vs. controls was 10 vs. 2 (p < 0.0001) and 9 vs. 1 days (p < 0.0001), respectively. Admission diagnosis of traumatic brain injury [adjusted odds ratio (OR): 5.6, 95% CI: 1.2-27.0; p = 0.03] and duration of mechanical ventilation (adjusted OR: 1.4, 95% CI: 1.3-1.5; p < 0.0001) were independently associated with A. baumannii aquisition. CONCLUSION: Acinetobacter baumannii acquisition was common and associated with increased morbidity, but not increased mortality.
OBJECTIVES: To describe and compare characteristics and outcomes of patients colonized or infected with Acinetobacter baumannii (cases) to a control group. METHODS: A retrospective case-controlled study of patients admitted to a South African paediatric intensive care unit (PICU) between January and December 2010. RESULTS:Acinetobacter baumannii was isolated in 194 patients. Mortality was similar between cases (9.3%) and controls (9.8%). Median duration of PICU stay and mechanical ventilation in cases vs. controls was 10 vs. 2 (p < 0.0001) and 9 vs. 1 days (p < 0.0001), respectively. Admission diagnosis of traumatic brain injury [adjusted odds ratio (OR): 5.6, 95% CI: 1.2-27.0; p = 0.03] and duration of mechanical ventilation (adjusted OR: 1.4, 95% CI: 1.3-1.5; p < 0.0001) were independently associated with A. baumannii aquisition. CONCLUSION:Acinetobacter baumannii acquisition was common and associated with increased morbidity, but not increased mortality.