Literature DB >> 2583279

Conserved residues of tumour necrosis factor and lymphotoxin constitute the framework of the trimeric structure.

J Tavernier1, X van Ostade, G Hauquier, T Prange, I Lasters, M de Maeyer, A Lewit-Bentley, R Fourme.   

Abstract

Four distinct areas of primary sequence conservation between known tumour necrosis factor and lymphotoxin polypeptides from various species can be recognized. When these amino acid sequences are highlighted in the three-dimensional structure, all are found in the same region, constituting the framework of the trimeric structure.

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Year:  1989        PMID: 2583279     DOI: 10.1016/0014-5793(89)81560-1

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  1 in total

1.  Localization of the active site of human tumour necrosis factor (hTNF) by mutational analysis.

Authors:  X Van Ostade; J Tavernier; T Prangé; W Fiers
Journal:  EMBO J       Date:  1991-04       Impact factor: 11.598

  1 in total

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