Correction: characterization of the integration and modular excision of the integrative conjugative element PAISt in Streptomyces turgidiscabies Car8.

In Fig. 1, the names of the genes nec1 and tomA are swapped. Please see the corrected Fig. 1 here.

Fig 1

Schematic representation of the PAISt in S. turgidiscabies Car8.

Copies of the 3′ end of the bacitracin resistance gene (bacA) delimit the element in two modules of 105 Kb and 569 Kb. The virulence genes nec1 and tomA are located in the first module and the fasciation (fas) and thaxtomin (txt) biosynthetic clusters are located in the second module. The putative integrase (intSt) is located at the 3′ end of the island. The 8 bp palidromic repeats are shown within the bacA gene and its truncated copies.

In Fig. 8, the names of the genes nec1 and tomA are swapped. Please see the corrected Fig. 8 here.

Fig 8

Relationships of PAISt with PAISs1 in S. scabies 87–22 and PAISa1 in S. acidiscabies 84–104.

Islands PAISs1 in S. scabies and PAISa1 in S. acidiscabies, are integrated at the bacA 3′ end and contain a remnant of the intSt (red line arrow) delimited by a degenerate version of the 8 bp palindrome, (mutated residues are in red). Both islands are identical to the 105 Kb module of PAISt. The thaxtomin biosynthesis cluster (txt) is conserved inS. scabies and S. acidiscabies but is not linked to the 105 Kb island.