Literature DB >> 25830046

A 26-year-old female with metastatic primary gastrointestinal malignancy presenting as menorrhagia.

Maliha Khan1, Ravinder Pal Bhatti1, Sarbajit Mukherjee1, Alaa M Ali1, Alan D Gilman1, Aibek E Mirrakhimov1, Nkemakolam Iroegbu1.   

Abstract

Krukenberg tumor is a metastatic malignant tumor of the ovary arising from a wide variety of primary sources, with the stomach being the most common. The presenting symptoms are non-specific and the primary source is often un-identified. Here, we describe a case of a 26-year-old Hispanic gravida 4, para 3 female who presented to our hospital with dysuria, pelvic pain and irregular, heavy menstrual cycles for three months duration. An endometrial biopsy was suggestive of carcinosarcoma. The patient underwent debulking surgery with partial cystectomy and bladder repair. A week later, she presented with hematemesis and an endoscopic biopsy revealed a diagnosis of poorly differentiated gastric adenocarcinoma. The tissue specimen obtained during the initial surgery was identified as Krukenberg tumor. The patient underwent adjuvant chemotherapy with FOLFOX along with gastrectomy with intraperitoneal chemotherapy.

Entities:  

Keywords:  Krukenberg tumor; menorrhagia

Year:  2015        PMID: 25830046      PMCID: PMC4311099          DOI: 10.3978/j.issn.2078-6891.2014.080

Source DB:  PubMed          Journal:  J Gastrointest Oncol        ISSN: 2078-6891


  17 in total

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Journal:  Am J Obstet Gynecol       Date:  1968-04-15       Impact factor: 8.661

Review 5.  From krukenberg to today: the ever present problems posed by metastatic tumors in the ovary: part I. Historical perspective, general principles, mucinous tumors including the krukenberg tumor.

Authors:  Robert H Young
Journal:  Adv Anat Pathol       Date:  2006-09       Impact factor: 3.875

6.  Preoperative findings in non-gynecologic carcinomas metastasizing to the ovaries.

Authors:  Fumitaka Kikkawa; Kiyosumi Shibata; Kazuhiko Ino; Seiji Nomura; Hiroaki Kajiyama; Takahiro Suzuki; Michiyasu Kawai; Shigehiko Mizutani
Journal:  Gynecol Obstet Invest       Date:  2002       Impact factor: 2.031

Review 7.  An in-depth look at Krukenberg tumor: an overview.

Authors:  Osama M Al-Agha; Anthony D Nicastri
Journal:  Arch Pathol Lab Med       Date:  2006-11       Impact factor: 5.534

8.  Immunohistochemical characterization of signet-ring cell carcinomas of the stomach, breast, and colon.

Authors:  Peiguo G Chu; Lawrence M Weiss
Journal:  Am J Clin Pathol       Date:  2004-06       Impact factor: 2.493

9.  Ovarian metastases: computed tomographic appearances.

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Journal:  Radiology       Date:  1985-07       Impact factor: 11.105

10.  Prevention of peritoneal metastasis of human gastric cancer cells in nude mice by S-1, a novel oral derivative of 5-Fluorouracil.

Authors:  Takuji Mori; Yoshiyuki Fujiwara; Masahiko Yano; Shigeyuki Tamura; Takushi Yasuda; Shuji Takiguchi; Morito Monden
Journal:  Oncology       Date:  2003       Impact factor: 2.935

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