Literature DB >> 25830044

Numb chin syndrome secondary to leptomeningeal carcinomatosis from gastric adenocarcinoma.

Vincent J Riesgo1, Silvia R Delgado1, Julio Poveda1, Kottil Rammohan1.   

Abstract

Numb chin syndrome (NCS) can be a sign of malignancy. Its association with gastric adenocarcinoma is rare. We report a case of a 27-year-old Hispanic female that presented with complaint of left sided headache associated with numbness of the left side of chin and lower gingiva. Initial brain MRI, whole body gallium scan, high resolution CT of chest and elevated protein in the CSF were suggestive of sarcoidosis. She was treated with IV steroids with transient clinical improvement. Two weeks later, her symptoms worsened and further evaluation revealed the diagnosis of a poorly differentiated metastatic gastric adenocarcinoma with leptomeningeal involvement. This case report aims to emphasize the importance of identifying NCS as a possible indication of an underlying malignant condition. Reported cases of NCS associated with metastatic gastric adenocarcinoma are very rare.

Entities:  

Keywords:  Numb chin syndrome (NCS); gastric adenocarcinoma; leptomeningeal carcinomatosis (LMC); mental nerve neuropathy; sarcoidosis

Year:  2015        PMID: 25830044      PMCID: PMC4311085          DOI: 10.3978/j.issn.2078-6891.2014.076

Source DB:  PubMed          Journal:  J Gastrointest Oncol        ISSN: 2078-6891


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