Literature DB >> 25829569

Evaluation of antioxidant activities of bioactive compounds and various extracts obtained from saffron (Crocus sativus L.): a review.

Somayeh Rahaiee1, Sohrab Moini1, Maryam Hashemi2, Seyed Abbas Shojaosadati3.   

Abstract

Saffron (Crocus sativus L. stigma), the most valuable medicinal food product, belongs to the Iridaceae family which has been widely used as a coloring and flavoring agent. These properties are basically related to its crocins, picrocrocin and safranal contents which have all demonstrated health promoting properties. The present review article highlights the phytochemical constituents (phenolic and flavonoid compounds, degraded carotenoid compounds crocins and crocetin) that are important in antioxidant activity of saffron extracts. However, the synergistic effect of all the bioactive components presence in saffron gave a significant antioxidant activity similar to vegetables rich in carotenoids. Our study provides an updated overview focused on the antioxidant activity of saffron related to its bioactive compounds to design the different functional products in food, medicine and cosmetic industries.

Entities:  

Keywords:  Antioxidant activity; Bioactive compounds; Saffron; Saffron extracts

Year:  2014        PMID： 25829569      PMCID： PMC4375186          DOI： 10.1007/s13197-013-1238-x

Source DB:  PubMed          Journal:  J Food Sci Technol        ISSN： 0022-1155            Impact factor:   2.701


  37 in total

1.  Antioxidant capacity of 26 spice extracts and characterization of their phenolic constituents.

Authors:  Bin Shan; Yizhong Z Cai; Mei Sun; Harold Corke
Journal:  J Agric Food Chem       Date:  2005-10-05       Impact factor: 5.279

2.  Further examination of antiradical properties of Crocus sativus stigmas extract rich in crocins.

Authors:  Stella A Ordoudi; Christina D Befani; Nikolaos Nenadis; George G Koliakos; Maria Z Tsimidou
Journal:  J Agric Food Chem       Date:  2009-04-22       Impact factor: 5.279

3.  Radical scavenging activity and LC-MS metabolic profiling of petals, stamens, and flowers of Crocus sativus L.

Authors:  Paola Montoro; Mariateresa Maldini; Leonilda Luciani; Carlo I G Tuberoso; Francesca Congiu; Cosimo Pizza
Journal:  J Food Sci       Date:  2012-07-18       Impact factor: 3.167

4.  Protective effects of saffron extract and its active constituent crocin against oxidative stress and spatial learning and memory deficits induced by chronic stress in rats.

Authors:  Behshid Ghadrdoost; Abbas Ali Vafaei; Ali Rashidy-Pour; Razieh Hajisoltani; Ahmad Reza Bandegi; Fareshteh Motamedi; Saeed Haghighi; Hamid Reza Sameni; Sharzad Pahlvan
Journal:  Eur J Pharmacol       Date:  2011-05-18       Impact factor: 4.432

5.  Memory enhancing effects of saffron in aged mice are correlated with antioxidant protection.

Authors:  Magdalini A Papandreou; Maria Tsachaki; Spiros Efthimiopoulos; Paul Cordopatis; Fotini N Lamari; Marigoula Margarity
Journal:  Behav Brain Res       Date:  2011-01-14       Impact factor: 3.332

6.  Orally administered crocetin and crocins are absorbed into blood plasma as crocetin and its glucuronide conjugates in mice.

Authors:  Akira Asai; Takahisa Nakano; Masahiro Takahashi; Akihiko Nagao
Journal:  J Agric Food Chem       Date:  2005-09-07       Impact factor: 5.279

7.  Effect of dietary saffron (Crocus sativus L.) on the oxidative stability of egg yolk.

Authors:  N A Botsoglou; P Florou-Paneri; I Nikolakakis; I Giannenas; V Dotas; E N Botsoglou; S Aggelopoulos
Journal:  Br Poult Sci       Date:  2005-12       Impact factor: 2.095

8.  Protective effect of aqueous saffron extract (Crocus sativus L.) and crocin, its active constituent, on renal ischemia-reperfusion-induced oxidative damage in rats.

Authors:  Hossein Hosseinzadeh; Hamid R Sadeghnia; Toktam Ziaee; Aghdas Danaee
Journal:  J Pharm Pharm Sci       Date:  2005-08-22       Impact factor: 2.327

9.  Radical scavenging activity of Crocus sativus L. extract and its bioactive constituents.

Authors:  A N Assimopoulou; Z Sinakos; V P Papageorgiou
Journal:  Phytother Res       Date:  2005-11       Impact factor: 5.878

10.  Inhibitory activity on amyloid-beta aggregation and antioxidant properties of Crocus sativus stigmas extract and its crocin constituents.

Authors:  Magdalini A Papandreou; Charalambos D Kanakis; Moschos G Polissiou; Spyros Efthimiopoulos; Paul Cordopatis; Marigoula Margarity; Fotini N Lamari
Journal:  J Agric Food Chem       Date:  2006-11-15       Impact factor: 5.279
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  24 in total

1.  Safranal protects against beta-amyloid peptide-induced cell toxicity in PC12 cells via MAPK and PI3 K pathways.

Authors:  Faezeh Rafieipour; Elham Hadipour; Seyed Ahmad Emami; Javad Asili; Zahra Tayarani-Najaran
Journal:  Metab Brain Dis       Date:  2018-11-06       Impact factor: 3.584

2.  Neuroprotective effect of Crocus sativus against cerebral ischemia in rats.

Authors:  Rehab F Abdel-Rahman; Sally A El Awdan; Rehab R Hegazy; Dina F Mansour; H A Ogaly; Marwan Abdelbaset
Journal:  Metab Brain Dis       Date:  2019-11-14       Impact factor: 3.584

Review 3.  Critical Review on Nutritional, Bioactive, and Medicinal Potential of Spices and Herbs and Their Application in Food Fortification and Nanotechnology.

Authors:  Debopriya Mandal; Tanmay Sarkar; Runu Chakraborty
Journal:  Appl Biochem Biotechnol       Date:  2022-10-11       Impact factor: 3.094

4.  An In Vitro Study of Saffron Carotenoids: The Effect of Crocin Extracts and Dimethylcrocetin on Cancer Cell Lines.

Authors:  Kyriaki Hatziagapiou; Olti Nikola; Sofia Marka; Eleni Koniari; Eleni Kakouri; Maria-Eleftheria Zografaki; Sophie S Mavrikou; Charalabos Kanakis; Emmanouil Flemetakis; George P Chrousos; Spyridon Kintzios; George I Lambrou; Christina Kanaka-Gantenbein; Petros A Tarantilis
Journal:  Antioxidants (Basel)       Date:  2022-05-28

5.  Lipid, Aqueous and Mucin Tear Film Layer Stability and Permanence within 0.15% Liposome Crosslinked Hyaluronic Acid versus 0.15% Non-Crosslinked Hyaluronic Acid Measured with a Novel Non-Invasive Ocular Surface Analyzer.

Authors:  José-María Sánchez-González; Concepción De-Hita-Cantalejo; Concepción Martínez-Lara; María Carmen Sánchez-González
Journal:  J Clin Med       Date:  2022-06-27       Impact factor: 4.964

6.  Characterization of phenolics, amino acids, fatty acids and antioxidant activity in pulp and seeds of high altitude Himalayan crab apple fruits (Malus baccata).

Authors:  Vikas Dadwal; Himani Agrawal; Kanika Sonkhla; Robin Joshi; Mahesh Gupta
Journal:  J Food Sci Technol       Date:  2018-03-24       Impact factor: 2.701

Review 7.  Anti-Depressant Properties of Crocin Molecules in Saffron.

Authors:  Shahida Anusha Siddiqui; Ali Ali Redha; Edgar Remmet Snoeck; Shubhra Singh; Jesus Simal-Gandara; Salam A Ibrahim; Seid Mahdi Jafari
Journal:  Molecules       Date:  2022-03-23       Impact factor: 4.411

8.  The effects of crocin, insulin and their co-administration on the heart function and pathology in streptozotocin-induced diabetic rats.

Authors:  Amir Abbas Farshid; Esmaeal Tamaddonfard; Masoumeh Moradi-Arzeloo; Navideh Mirzakhani
Journal:  Avicenna J Phytomed       Date:  2016 Nov-Dec

9.  The influence of different drying methods on constituents and antioxidant activity of saffron from china.

Authors:  Yingpeng Tong; Xingyi Zhu; Yongqiu Yan; Ruoxi Liu; Feng Gong; Ling Zhang; Jiangning Hu; Ling Fang; Ruwei Wang; Ping Wang
Journal:  Int J Anal Chem       Date:  2015-03-30       Impact factor: 1.885

10.  The Efficacy of Crocin of Saffron (Crocus sativus L.) on the Components of Metabolic Syndrome: A Randomized Controlled Clinical Trial.

Authors:  Tayyebe Kermani; Toba Kazemi; Somayye Molki; Khadije Ilkhani; Gholamreza Sharifzadeh; Omid Rajabi
Journal:  J Res Pharm Pract       Date:  2017 Oct-Dec
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