Damla Erginturk Acar1, Ugur Acar2, Zuhal Ozen Tunay3, Ozdemir Ozdemir3, Anil Dolgun4, Mesut Erdurmus2. 1. Department of Ophthalmology, Zekai Tahir Burak Women's Health Research and Education Hospital, Ankara, Turkey. Electronic address: erginturk@yahoo.com. 2. Department of Ophthalmology, Hacettepe University, Faculty of Medicine, Ankara, Turkey. 3. Department of Ophthalmology, Zekai Tahir Burak Women's Health Research and Education Hospital, Ankara, Turkey. 4. Department of Biostatistics, Hacettepe University, Faculty of Medicine.
Abstract
PURPOSE: To describe the normal values of intraocular pressure (IOP) and central corneal thickness (CCT) in healthy premature infants. METHODS: Infants of <32 weeks' gestational age who underwent screened for retinopathy of prematurity were prospectively enrolled. The same ophthalmologist measured IOP by applanation tonometry and CCT using ultrasonic pachymetry. Infants were divided into four groups according to postconceptional ages (PCA). The mean values of the IOP and CCT were compared by nonparametric statistical tests, and the relationship of the PCA with IOP and CCT were analyzed with correlation tests. Only right eye measurements were analyzed. RESULTS: A total of 470 infants (mean PCA, 35.94 ± 4.00 weeks) were enrolled. The mean IOP with standard deviation was 16.86 ± 2.93 mm Hg; the mean CCT, 590 ± 58.26 μm. Both IOP and CCT values were found to be significantly higher in infants with lower versus higher PCA (P < 0.001). There was a statistically significant negative linear relationship between the PCA and the values of IOP and CCT, separately. CONCLUSIONS: IOP and CCT values may be higher in infants with lower PCA. Higher IOP values in these infants may be associated with higher CCT values.
PURPOSE: To describe the normal values of intraocular pressure (IOP) and central corneal thickness (CCT) in healthy premature infants. METHODS:Infants of <32 weeks' gestational age who underwent screened for retinopathy of prematurity were prospectively enrolled. The same ophthalmologist measured IOP by applanation tonometry and CCT using ultrasonic pachymetry. Infants were divided into four groups according to postconceptional ages (PCA). The mean values of the IOP and CCT were compared by nonparametric statistical tests, and the relationship of the PCA with IOP and CCT were analyzed with correlation tests. Only right eye measurements were analyzed. RESULTS: A total of 470 infants (mean PCA, 35.94 ± 4.00 weeks) were enrolled. The mean IOP with standard deviation was 16.86 ± 2.93 mm Hg; the mean CCT, 590 ± 58.26 μm. Both IOP and CCT values were found to be significantly higher in infants with lower versus higher PCA (P < 0.001). There was a statistically significant negative linear relationship between the PCA and the values of IOP and CCT, separately. CONCLUSIONS: IOP and CCT values may be higher in infants with lower PCA. Higher IOP values in these infants may be associated with higher CCT values.
Authors: May May Choo; Choo Mee Yeong; John R Grigg; Nurliza Khaliddin; Azida Juana Kadir; Elizabeth H Barnes; Tengku Ain Kamalden; Stephanie L Watson Journal: Medicine (Baltimore) Date: 2018-11 Impact factor: 1.817