Literature DB >> 25828806

Mechanistic overview of ADP-ribosylation reactions.

Vicky M-H Sung1.   

Abstract

ADP-ribosylation reactions consist of mono-ADP-ribosylation, poly-ADP-ribosylation and cyclic ADP-ribosylation. These reactions play essential roles in many important physiological and pathophysiological events. The types of chemical linkages, the evolutionarily conserved motif within the enzymes to determine the target specificity, stereochemistry of the ADP-ribosylated products, and the chemical reactions taking place among the enzymes and substrates are discussed.
Copyright © 2015 Elsevier B.V. and Société Française de Biochimie et Biologie Moléculaire (SFBBM). All rights reserved.

Entities:  

Keywords:  ADP-ribosylation; Cyclic ADP-ribosylation; Mono-ADP-ribosylation; NAD(+); Poly-ADP-ribosylation; Schiff base

Mesh:

Substances:

Year:  2015        PMID: 25828806     DOI: 10.1016/j.biochi.2015.03.016

Source DB:  PubMed          Journal:  Biochimie        ISSN: 0300-9084            Impact factor:   4.079


  5 in total

Review 1.  Novel drug targets for personalized precision medicine in relapsed/refractory diffuse large B-cell lymphoma: a comprehensive review.

Authors:  Rosalba Camicia; Hans C Winkler; Paul O Hassa
Journal:  Mol Cancer       Date:  2015-12-11       Impact factor: 27.401

2.  DNA Repair Factor Poly(ADP-Ribose) Polymerase 1 Is a Proviral Factor in Hepatitis B Virus Covalently Closed Circular DNA Formation.

Authors:  Yingshan Chen; Yongxuan Yao; Kaitao Zhao; Canyu Liu; Yifei Yuan; Hao Sun; Dan Huang; Yi Zheng; Yuan Zhou; Jizheng Chen; Yun Wang; Chunchen Wu; Bixiang Zhang; Yujuan Guan; Feng Li; Rongjuan Pei; Xinwen Chen
Journal:  J Virol       Date:  2022-06-07       Impact factor: 6.549

3.  (ADP-ribosyl)hydrolases: Structural Basis for Differential Substrate Recognition and Inhibition.

Authors:  Johannes Gregor Matthias Rack; Antonio Ariza; Bryon S Drown; Callum Henfrey; Edward Bartlett; Tomohiro Shirai; Paul J Hergenrother; Ivan Ahel
Journal:  Cell Chem Biol       Date:  2018-11-21       Impact factor: 8.116

Review 4.  Common Mechanism for Target Specificity of Protein- and DNA-Targeting ADP-Ribosyltransferases.

Authors:  Toru Yoshida; Hideaki Tsuge
Journal:  Toxins (Basel)       Date:  2021-01-07       Impact factor: 4.546

5.  OZITX, a pertussis toxin-like protein for occluding inhibitory G protein signalling including Gαz.

Authors:  Alastair C Keen; Maria Hauge Pedersen; Laura Lemel; Daniel J Scott; Meritxell Canals; Dene R Littler; Travis Beddoe; Yuki Ono; Lei Shi; Asuka Inoue; Jonathan A Javitch; J Robert Lane
Journal:  Commun Biol       Date:  2022-03-23
  5 in total

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