| Literature DB >> 25828806 |
Abstract
ADP-ribosylation reactions consist of mono-ADP-ribosylation, poly-ADP-ribosylation and cyclic ADP-ribosylation. These reactions play essential roles in many important physiological and pathophysiological events. The types of chemical linkages, the evolutionarily conserved motif within the enzymes to determine the target specificity, stereochemistry of the ADP-ribosylated products, and the chemical reactions taking place among the enzymes and substrates are discussed.Entities:
Keywords: ADP-ribosylation; Cyclic ADP-ribosylation; Mono-ADP-ribosylation; NAD(+); Poly-ADP-ribosylation; Schiff base
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Year: 2015 PMID: 25828806 DOI: 10.1016/j.biochi.2015.03.016
Source DB: PubMed Journal: Biochimie ISSN: 0300-9084 Impact factor: 4.079