Literature DB >> 25827631

The ambidextrous cyclooxygenase: an enduring target.

Mayank Bapna1, Lalit Singh Chauhan.   

Abstract

With the discovery of COX, pain has not been treated in a relentless manner. Numbers of drugs with fewer side effects were discovered and are used successfully for treatment of pain. With new research coming into being since the discovery of COX, it was established that COX can be targeted not only for treatment of pain but for curing various diseases like cancer, Alzheimer's, Parkinson's disease, Glaucoma etc. With the sighting of COX-3, another isoform of COX, new diseases are being targeted for better treatment.

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Year:  2015        PMID： 25827631     DOI： 10.2174/1871528114666150401105545

Source DB:  PubMed          Journal:  Inflamm Allergy Drug Targets        ISSN： 1871-5281


  5 in total

1.  The Role of Cyclooxygenase Enzymes in the Effects of Losartan and Lisinopril on the Contractions of Rat Thoracic Aorta.

Authors:  Fikriye Yasemin Ozatik; Bilgin Kaygisiz; Kevser Erol
Journal:  Eurasian J Med       Date:  2017-02

2.  The arachidonic acid metabolism protein-protein interaction network and its expression pattern in esophageal diseases.

Authors:  Bingli Wu; Chunying Bai; Zepeng Du; Haiying Zou; Jianyi Wu; Wenming Xie; Pixian Zhang; Liyan Xu; Enmin Li
Journal:  Am J Transl Res       Date:  2018-03-15       Impact factor: 4.060

Review 3.  Could Aspirin and Diets High in Fiber Act Synergistically to Reduce the Risk of Colon Cancer in Humans?

Authors:  Pan Pan; Yi-Wen Huang; Kiyoko Oshima; Martha Yearsley; Jianying Zhang; Jianhua Yu; Mark Arnold; Li-Shu Wang
Journal:  Int J Mol Sci       Date:  2018-01-06       Impact factor: 5.923

4.  Cytosolic phospholipase A2-α participates in lipid body formation and PGE2 release in human neutrophils stimulated with an L-amino acid oxidase from Calloselasma rhodostoma venom.

Authors:  Mauro Valentino Paloschi; Jéssica Amaral Lopes; Charles Nunes Boeno; Milena Daniela Souza Silva; Jaína Rodrigues Evangelista; Adriana Silva Pontes; Sulamita da Silva Setúbal; Cristina Matiele Alves Rego; Neriane Monteiro Néry; Alex Augusto Ferreira E Ferreira; Weverson Luciano Pires; Kátia Paula Felipin; Gabriel Eduardo Melim Ferreira; Patrícia Torres Bozza; Juliana Pavan Zuliani
Journal:  Sci Rep       Date:  2020-07-03       Impact factor: 4.379

Review 5.  Lipid Droplets, the Central Hub Integrating Cell Metabolism and the Immune System.

Authors:  Wei Zhang; Linyong Xu; Ling Zhu; Yifan Liu; Siwei Yang; Mingyi Zhao
Journal:  Front Physiol       Date:  2021-12-03       Impact factor: 4.566
  5 in total

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