Literature DB >> 25825614

Improving the dielectric properties of an electrowetting-on-dielectric microfluidic device with a low-pressure chemical vapor deposited Si3N4 dielectric layer.

Hsien-Hua Shen1, Lung-Yuan Chung1, Da-Jeng Yao.   

Abstract

Dielectric breakdown is a common problem in a digital microfluidic system, which limits its application in chemical or biomedical applications. We propose a new fabrication of an electrowetting-on-dielectric (EWOD) device using Si3N4 deposited by low-pressure chemical vapor deposition (LPCVD) as a dielectric layer. This material exhibits a greater relative permittivity, purity, uniformity, and biocompatibility than polymeric films. These properties also increase the breakdown voltage of a dielectric layer and increase the stability of an EWOD system when applied in biomedical research. Medium droplets with mouse embryos were manipulated in this manner. The electrical properties of the Si3N4 dielectric layer-breakdown voltage, refractive index, relative permittivity, and variation of contact angle with input voltage-were investigated and compared with a traditional Si3N4 dielectric layer deposited as a plasma-enhanced chemical vapor deposition to confirm the potential of LPCVD Si3N4 applied as the dielectric layer of an EWOD digital microfluidic system.

Entities:  

Year:  2015        PMID: 25825614      PMCID: PMC4376753          DOI: 10.1063/1.4915613

Source DB:  PubMed          Journal:  Biomicrofluidics        ISSN: 1932-1058            Impact factor:   2.800


  14 in total

1.  Low voltage electrowetting using thin fluoroploymer films.

Authors:  Shaun Berry; Jakub Kedzierski; Behrouz Abedian
Journal:  J Colloid Interface Sci       Date:  2006-08-10       Impact factor: 8.128

2.  On-chip drop-to-drop liquid microextraction coupled with real-time concentration monitoring technique.

Authors:  Pavithra A L Wijethunga; Yasith S Nanayakkara; Praveen Kunchala; Daniel W Armstrong; Hyejin Moon
Journal:  Anal Chem       Date:  2011-02-04       Impact factor: 6.986

3.  Biofunctionalization of electrowetting-on-dielectric digital microfluidic chips for miniaturized cell-based applications.

Authors:  Daan Witters; Nicolas Vergauwe; Steven Vermeir; Frederik Ceyssens; Sandra Liekens; Robert Puers; Jeroen Lammertyn
Journal:  Lab Chip       Date:  2011-07-01       Impact factor: 6.799

4.  Coplanar electrowetting-induced stirring as a tool to manipulate biological samples in lubricated digital microfluidics. Impact of ambient phase on drop internal flow pattern.

Authors:  Laurent Davoust; Yves Fouillet; Rachid Malk; Johannes Theisen
Journal:  Biomicrofluidics       Date:  2013-07-25       Impact factor: 2.800

5.  Incubated protein reduction and digestion on an electrowetting-on-dielectric digital microfluidic chip for MALDI-MS.

Authors:  Wyatt C Nelson; Ivory Peng; Geun-An Lee; Joseph A Loo; Robin L Garrell; Chang-Jin C J Kim
Journal:  Anal Chem       Date:  2010-11-08       Impact factor: 6.986

6.  A digital microfluidic platform for primary cell culture and analysis.

Authors:  Suthan Srigunapalan; Irwin A Eydelnant; Craig A Simmons; Aaron R Wheeler
Journal:  Lab Chip       Date:  2011-11-18       Impact factor: 6.799

7.  Electrowetting on dielectric experiments using graphene.

Authors:  Xuebin Tan; Zhixian Zhou; Mark Ming-Cheng Cheng
Journal:  Nanotechnology       Date:  2012-08-24       Impact factor: 3.874

8.  Low voltage picoliter droplet manipulation utilizing electrowetting-on-dielectric platforms.

Authors:  Yan-You Lin; Erin R F Welch; Richard B Fair
Journal:  Sens Actuators B Chem       Date:  2012-10       Impact factor: 7.460

9.  How to make water run uphill.

Authors:  M K Chaudhury; G M Whitesides
Journal:  Science       Date:  1992-06-12       Impact factor: 47.728

10.  Improvement in the breakdown properties of electrowetting using polyelectrolyte ionic solution.

Authors:  Seungyul Choi; Yongjoo Kwon; Yoon-Sun Choi; Eok Su Kim; Jungmok Bae; Junghoon Lee
Journal:  Langmuir       Date:  2012-12-14       Impact factor: 3.882

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  4 in total

1.  Preface to Special Topic: Select Papers from the 8th IEEE International Conference on Nano/Molecular Medicine and Engineering Held in Kaohsiung, Taiwan.

Authors:  Da-Jeng Yao; Chao-Min Cheng
Journal:  Biomicrofluidics       Date:  2015-04-28       Impact factor: 2.800

2.  Droplet Velocity Measurement Based on Dielectric Layer Thickness Variation Using Digital Microfluidic Devices.

Authors:  Siti Noor Idora Syafinaz Zulkepli; Nor Hisham Hamid; Vineeta Shukla
Journal:  Biosensors (Basel)       Date:  2018-05-08

3.  Aluminum doped zinc oxide deposited by atomic layer deposition and its applications to micro/nano devices.

Authors:  Nguyen Van Toan; Truong Thi Kim Tuoi; Naoki Inomata; Masaya Toda; Takahito Ono
Journal:  Sci Rep       Date:  2021-01-13       Impact factor: 4.379

4.  Identification of Microorganisms Using an EWOD System.

Authors:  Jung-Cheng Su; Yi-Ju Liu; Da-Jeng Yao
Journal:  Micromachines (Basel)       Date:  2022-01-26       Impact factor: 2.891

  4 in total

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