Carmen Montaño-Remacha1, María Dolores Márquez-Cruz2, Pilar Hidalgo-Guzmán3, Antonio Sánchez-Porto4, Francisco de Paula Téllez-Pérez5. 1. Servicio de Epidemiología, Área de Gestión Sanitaria Campo de Gibraltar, Sistema Andaluz de Salud, Algeciras, España. Electronic address: cmontanno@gmail.com. 2. Servicio de Medicina Preventiva, Área de Gestión Sanitaria Campo de Gibraltar, Sistema Andaluz de Salud, La Línea de la Concepción, España. 3. Servicio de Nefrología, Área de Gestión Sanitaria Campo de Gibraltar, Sistema Andaluz de Salud, Algeciras, España. 4. Servicio de Microbiología, Área de Gestión Sanitaria Campo de Gibraltar, Sistema Andaluz de Salud, La Línea de la Concepción, España. 5. Servicio de Enfermedades Infecciosas, Área de Gestión Sanitaria Campo de Gibraltar, Sistema Andaluz de Salud, La Línea de la Concepción, España.
Abstract
INTRODUCTION: In January 2014 a possible outbreak of Burkholderia cepacia bacteremia occurred in a hemodialysis center situated in La Linea de la Concepción (Cadiz). An investigation was begun to confirm the outbreak, identify the source, and implement control measures. METHODS: A descriptive analysis was performed to describe the characteristics of the patients affected with Burkholderia cepacia bacteremia from November 2013 to February 2014. Environmental samples were taken. A molecular typing study was performed using pulsed field gel electrophoresis (SpeI PFGE) and MLST analysis in order to determine the genetic similarity between the isolates. RESULTS: The bacterium was isolated from blood cultures of 7 patients during the study period. Three of the samples (2 of which were also cases) were endoluminal fluid from catheter locks, and 4 chlorhexidine bottle samples. The patients were coincident in 2 of the 6 work shifts. The mean age of the cases was 67 years of whom 57% were women. Human samples and an environmental sample was analyzed and found to be genetically identical (ST653 clone). CONCLUSIONS: The analysis confirmed the outbreak of Burkholderia cepacia, with 7 cases among the patients of the hemodialysis center. The outbreak was due to the same strain, probably a common source and secondary transmission from person to person.
INTRODUCTION: In January 2014 a possible outbreak of Burkholderia cepacia bacteremia occurred in a hemodialysis center situated in La Linea de la Concepción (Cadiz). An investigation was begun to confirm the outbreak, identify the source, and implement control measures. METHODS: A descriptive analysis was performed to describe the characteristics of the patients affected with Burkholderia cepacia bacteremia from November 2013 to February 2014. Environmental samples were taken. A molecular typing study was performed using pulsed field gel electrophoresis (SpeI PFGE) and MLST analysis in order to determine the genetic similarity between the isolates. RESULTS: The bacterium was isolated from blood cultures of 7 patients during the study period. Three of the samples (2 of which were also cases) were endoluminal fluid from catheter locks, and 4 chlorhexidine bottle samples. The patients were coincident in 2 of the 6 work shifts. The mean age of the cases was 67 years of whom 57% were women. Human samples and an environmental sample was analyzed and found to be genetically identical (ST653 clone). CONCLUSIONS: The analysis confirmed the outbreak of Burkholderia cepacia, with 7 cases among the patients of the hemodialysis center. The outbreak was due to the same strain, probably a common source and secondary transmission from person to person.
Authors: Burke A Cunha; John Gian; Bertamaria Dieguez; Elsa Santos-Cruz; Daniela Matassa; Steve Gerson; Pat Daniels; Carlos Rosales; Rodger P Silletti Journal: J Clin Med Date: 2016-11-30 Impact factor: 4.241
Authors: Sally C Y Wong; Shuk-Ching Wong; Jonathan H K Chen; Rosana W S Poon; Derek L L Hung; Kelvin H Y Chiu; Simon Y C So; Wing Shan Leung; Tak Mao Chan; Desmond Y H Yap; Vivien W M Chuang; Kwok-Yung Yuen; Vincent C C Cheng Journal: Emerg Infect Dis Date: 2020-09 Impact factor: 6.883