Literature DB >> 25824287

Necrotising fasciitis secondary to perforated rectal adenocarcinoma presenting as a thigh swelling.

William David George Evans1, Conchubhair Winters2, Eshan Amin3.   

Abstract

A 62-year-old man was admitted to the medical admissions ward with right thigh pain presumed to be a deep vein thrombosis (DVT). Subsequent duplex ultrasonography excluded a DVT but noted the presence of a significant amount of subcutaneous gas. A plain film radiograph was performed with the same finding raising the possibility of necrotising fasciitis (NF). Only at this point was digital rectal examination performed revealing a large rectal mass oozing pus and blood. CT imaging showed thickening of the rectum consistent with a tumour with gas and fluid in the perirectal space extending to the anterolateral right femur. Despite aggressive debridement and treatment, the patient deteriorated and died 6 weeks later. This case should serve as a reminder to consider digital rectal examination and the occurrence of a rectal perforation in all patients who present with suspicious thigh swellings. 2015 BMJ Publishing Group Ltd.

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Year:  2015        PMID: 25824287      PMCID: PMC4386473          DOI: 10.1136/bcr-2014-208312

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  17 in total

1.  Hyperbaric oxygen therapy for necrotizing fasciitis reduces mortality and the need for debridements.

Authors:  J A Riseman; W A Zamboni; A Curtis; D R Graham; H R Konrad; D S Ross
Journal:  Surgery       Date:  1990-11       Impact factor: 3.982

Review 2.  Adjunctive hyperbaric oxygen for necrotizing fasciitis.

Authors:  Denny Levett; Michael H Bennett; Ian Millar
Journal:  Cochrane Database Syst Rev       Date:  2015-01-15

3.  Carcinomatous perforation of the sigmoid colon presenting as a thigh mass.

Authors:  T P Lam; N Maffulli; E H Chen; J C Cheng
Journal:  Bull Hosp Jt Dis       Date:  1996

4.  Synergistic necrotizing cellulitis.

Authors:  H H Stone; J D Martin
Journal:  Ann Surg       Date:  1972-05       Impact factor: 12.969

5.  Adjuvant hyperbaric oxygen therapy (HBO2)for treatment of necrotizing fasciitis reduces mortality and amputation rate.

Authors:  S J Escobar; J B Slade; T K Hunt; P Cianci
Journal:  Undersea Hyperb Med       Date:  2005 Nov-Dec       Impact factor: 0.698

6.  Intravenous immunoglobulin contains specific antibodies inhibitory to activation of T cells by staphylococcal toxin superantigens [see comment].

Authors:  S Takei; Y K Arora; S M Walker
Journal:  J Clin Invest       Date:  1993-02       Impact factor: 14.808

7.  Necrotizing fasciitis of the thigh should raise suspicion of a rectal cancer.

Authors:  H Khalil; B Tsilividis; L Schwarz; M Scotté
Journal:  J Visc Surg       Date:  2010-08-13       Impact factor: 2.043

8.  Traumatic rectal perforation presenting as necrotising fasciitis of the lower limb.

Authors:  W P Fu; H M Quah; K W Eu
Journal:  Singapore Med J       Date:  2009-08       Impact factor: 1.858

9.  Necrotising fasciitis of the thigh.

Authors:  K Haemers; R Peters; S Braak; F Wesseling
Journal:  BMJ Case Rep       Date:  2013-06-13

Review 10.  Necrotizing fasciitis.

Authors:  Rukshini Puvanendran; Jason Chan Meng Huey; Shanker Pasupathy
Journal:  Can Fam Physician       Date:  2009-10       Impact factor: 3.275

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  3 in total

1.  Necrotising fasciitis caused by metastatic endometrial cancer: a rare cause of a life-threatening condition.

Authors:  S Hendrickson; N Bystrzonowski; C Kokkinos; P Butler
Journal:  Ann R Coll Surg Engl       Date:  2016-11-21       Impact factor: 1.891

2.  Not your usual hip pain: necrotising fasciitis secondary to sigmoid perforation.

Authors:  Sarthak Soin; Sumathi Vijaya Rangan; Faisal Shaukat Ali; Chukwudumebi Okafor
Journal:  BMJ Case Rep       Date:  2019-03-14

3.  Necrotising Myofasciitis of the Lower Limb Secondary to Extra-Peritoneal Rectal Perforation.

Authors:  Mohamed A Radhi; Jamie Clements
Journal:  Cureus       Date:  2022-09-08
  3 in total

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