Literature DB >> 25822247

Correction: Rapid, accurate, and non-invasive measurement of zebrafish axial length and other eye dimensions using SD-OCT allows longitudinal analysis of myopia and emmetropization.

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Abstract

[This corrects the article DOI: 10.1371/journal.pone.0110699.].

Entities:  

Year:  2015        PMID: 25822247      PMCID: PMC4379152          DOI: 10.1371/journal.pone.0119779

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


There is an error in Fig. 3. Panels C and D were inadvertently omitted. The authors have provided the corrected figure below.
Fig 3

Eye size measurements can be normalized for comparison using body axis length or lens diameter.

A. Eye axial length in wild-type zebrafish has a good linear relationship to body axis length with points close to the best-fit trendline. lrp2 zebrafish axial length:body length ratios are mostly longer than wild-type, and show less correlation with the best-fit line. B. Eye axial length in wild-type zebrafish has an excellent linear relationship with lens diameter, while lrp2 zebrafish axial length:lens diameter ratios show less correlation with the best-fit line. C. Images of wild-type and lrp2 mutant zebrafish at 2 mpf. At this age, the lrp2 enlarged eye phenotype is not always obvious, and one fish can have emmetropic eye growth (lrp2 (normal eye size)) while another has enlarged, myopic eyes, with the left eye more affected than the right (lrp2 (large eye size)). OCT images of each eye are shown. D. Measurements taken from OCT images for each eye in C, as well as relative refractive error showing that only the lrp2 (large eye size) fish is myopic at this time.

Eye size measurements can be normalized for comparison using body axis length or lens diameter.

A. Eye axial length in wild-type zebrafish has a good linear relationship to body axis length with points close to the best-fit trendline. lrp2 zebrafish axial length:body length ratios are mostly longer than wild-type, and show less correlation with the best-fit line. B. Eye axial length in wild-type zebrafish has an excellent linear relationship with lens diameter, while lrp2 zebrafish axial length:lens diameter ratios show less correlation with the best-fit line. C. Images of wild-type and lrp2 mutant zebrafish at 2 mpf. At this age, the lrp2 enlarged eye phenotype is not always obvious, and one fish can have emmetropic eye growth (lrp2 (normal eye size)) while another has enlarged, myopic eyes, with the left eye more affected than the right (lrp2 (large eye size)). OCT images of each eye are shown. D. Measurements taken from OCT images for each eye in C, as well as relative refractive error showing that only the lrp2 (large eye size) fish is myopic at this time.
  1 in total

1.  Rapid, accurate, and non-invasive measurement of zebrafish axial length and other eye dimensions using SD-OCT allows longitudinal analysis of myopia and emmetropization.

Authors:  Ross F Collery; Kerry N Veth; Adam M Dubis; Joseph Carroll; Brian A Link
Journal:  PLoS One       Date:  2014-10-21       Impact factor: 3.240

  1 in total
  1 in total

1.  The association of TGFB1 genetic polymorphisms with high myopia: a systematic review and meta-analysis.

Authors:  Bo Meng; Shi-Ming Li; Yu Yang; Zhi-Rong Yang; Feng Sun; Meng-Tian Kang; Yun-Yun Sun; An-Ran Ran; Jia-Nan Wang; Ran Yan; Ya-Wen BaI; Ning-Li Wang; Si-Yan Zhan
Journal:  Int J Clin Exp Med       Date:  2015-11-15
  1 in total

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