Literature DB >> 25822218

Prefrontal dysfunction and a monkey model of schizophrenia.

Ping Mao1, Ding Cui, Xu-Dong Zhao, Yuan-Ye Ma.   

Abstract

The prefrontal cortex is implicated in cognitive functioning and schizophrenia. Prefrontal dysfunction is closely associated with the symptoms of schizophrenia. In addition to the features typical of schizophrenia, patients also present with aspects of cognitive disorders. Based on these relationships, a monkey model mimicking the cognitive symptoms of schizophrenia has been made using treatment with the non-specific competitive N-methyl-D-aspartate receptor antagonist, phencyclidine. The symptoms are ameliorated by atypical antipsychotic drugs such as clozapine. The beneficial effects of clozapine on behavioral impairment might be a specific indicator of schizophrenia-related cognitive impairment.

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Year:  2015        PMID： 25822218      PMCID： PMC5563701          DOI： 10.1007/s12264-014-1506-4

Source DB:  PubMed          Journal:  Neurosci Bull        ISSN： 1995-8218            Impact factor:   5.203


  51 in total

1.  The alpha(2A)-adrenergic agonist guanfacine improves visuomotor associative learning in monkeys.

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Journal:  Neuropsychopharmacology       Date:  2004-01       Impact factor: 7.853

Review 2.  Neurobiology of executive functions: catecholamine influences on prefrontal cortical functions.

Authors:  Amy F T Arnsten; Bao-Ming Li
Journal:  Biol Psychiatry       Date:  2005-06-01       Impact factor: 13.382

3.  The involvement of distraction in memory deficits induced by NMDAR antagonism: relevance to cognitive deficits in schizophrenia.

Authors:  Ben Grayson; Lisa Adamson; Michael Harte; Marianne Leger; Samuel Marsh; Chloe Piercy; Joanna C Neill
Journal:  Behav Brain Res       Date:  2014-03-13       Impact factor: 3.332

4.  Impaired performance on the object retrieval-detour test of executive function in the SIV/macaque model of AIDS.

Authors:  Rachel A Gray; Kristin M Wilcox; M Christine Zink; Michael R Weed
Journal:  AIDS Res Hum Retroviruses       Date:  2006-10       Impact factor: 2.205

Review 5.  Topography of cognition: parallel distributed networks in primate association cortex.

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Journal:  Annu Rev Neurosci       Date:  1988       Impact factor: 12.449

Review 6.  Frontal lobes.

Authors:  J M Fuster
Journal:  Curr Opin Neurobiol       Date:  1993-04       Impact factor: 6.627

Review 7.  The role of the hippocampo-prefrontal cortex system in phencyclidine-induced psychosis: a model for schizophrenia.

Authors:  Eiichi Jodo
Journal:  J Physiol Paris       Date:  2013-06-17

8.  Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos.

Authors:  Yuyu Niu; Bin Shen; Yiqiang Cui; Yongchang Chen; Jianying Wang; Lei Wang; Yu Kang; Xiaoyang Zhao; Wei Si; Wei Li; Andy Peng Xiang; Jiankui Zhou; Xuejiang Guo; Ye Bi; Chenyang Si; Bian Hu; Guoying Dong; Hong Wang; Zuomin Zhou; Tianqing Li; Tao Tan; Xiuqiong Pu; Fang Wang; Shaohui Ji; Qi Zhou; Xingxu Huang; Weizhi Ji; Jiahao Sha
Journal:  Cell       Date:  2014-01-30       Impact factor: 41.582

9.  Decreased prefrontal dopamine D1 receptors in schizophrenia revealed by PET.

Authors:  Y Okubo; T Suhara; K Suzuki; K Kobayashi; O Inoue; O Terasaki; Y Someya; T Sassa; Y Sudo; E Matsushima; M Iyo; Y Tateno; M Toru
Journal:  Nature       Date:  1997-02-13       Impact factor: 49.962

10.  Comparison of human ventral frontal cortex areas for cognitive control and language with areas in monkey frontal cortex.

Authors:  Franz-Xaver Neubert; Rogier B Mars; Adam G Thomas; Jerome Sallet; Matthew F S Rushworth
Journal:  Neuron       Date:  2014-01-28       Impact factor: 17.173
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  4 in total

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Journal:  Neurosci Bull       Date:  2015-04       Impact factor: 5.203

2.  Prepulse Inhibition of Auditory Cortical Responses in the Caudolateral Superior Temporal Gyrus in Macaca mulatta.

Authors:  Zuyue Chen; Lauri Parkkonen; Jingkuan Wei; Jin-Run Dong; Yuanye Ma; Synnöve Carlson
Journal:  Neurosci Bull       Date:  2017-10-11       Impact factor: 5.203

3.  MiR-4763-3p targeting RASD2as a Potential Biomarker and Therapeutic Target for Schizophrenia.

Authors:  Jiao Wang; Wenxin Qi; Hongwei Shi; Lin Huang; Fujiang Ning; Fushuai Wang; Kai Wang; Haotian Bai; Hao Wu; Junyi Zhuang; Huanle Hong; Haicong Zhou; Hu Feng; Yinping Zhou; Naijun Dong; Li Liu; Yanyan Kong; Jiang Xie; Robert Chunhua Zhao
Journal:  Aging Dis       Date:  2022-07-11       Impact factor: 9.968

Review 4.  A framework for the investigation of rare genetic disorders in neuropsychiatry.

Authors:  Stephan J Sanders; Mustafa Sahin; Joseph Hostyk; Audrey Thurm; Sebastien Jacquemont; Paul Avillach; Elise Douard; Christa L Martin; Meera E Modi; Andres Moreno-De-Luca; Armin Raznahan; Alan Anticevic; Ricardo Dolmetsch; Guoping Feng; Daniel H Geschwind; David C Glahn; David B Goldstein; David H Ledbetter; Jennifer G Mulle; Sergiu P Pasca; Rodney Samaco; Jonathan Sebat; Anne Pariser; Thomas Lehner; Raquel E Gur; Carrie E Bearden
Journal:  Nat Med       Date:  2019-09-23       Impact factor: 53.440
  4 in total

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