Literature DB >> 25821530

Convergent Lines of Descent: Symptoms, Patterns, Constellations, and the Emergent Interface of Systems Biology and Chinese Medicine.

Volker Scheid1.   

Abstract

During the first decade of the twenty-first century, a network composed of politicians, regulators, bioscientists, clinical researchers, and Chinese medicine specialists has emerged that seeks to bridge an imagined gulf between the modern West and ancient China in order to create a new type of personalized medicine. The central building block of this bridge is the Chinese medical concept of zheng /, variously translated into English as syndrome, pattern, or type. My paper places side by side two different genealogies of how zheng assumed this central role. The first genealogy examines the process by means of which zheng came to be considered as something shared by both ancient China and cutting-edge biological science and, by extension, how it manages to hold together the entire institutional, political, and economic framework into which this bridge is embedded and which it co-creates. The second genealogy shows zheng to be central to a much older series of redefinitions of Chinese medicine and Chinese medical practice that extend from the eleventh century to the present. Read together, these two genealogies-neither of which should be seen as exhaustive-raise three important issues that are further discussed in the conclusion of the paper. First, I explore how the concept of zheng has come to tie a medical tradition derided by its adversaries for being a pseudoscience to one of the most cutting-edge fields of bioscience research. I ask what is at stake in this synthesis, for whom, and why, and how it transforms Chinese medicine and/or systems biology along the way. Second, I am interested in finding out how and why the very same concept can be at the heart of two apparently agonistic visions of Chinese medicine's future as it is popularly imagined in China today. Finally, I insist that the medical humanities need to become actively involved in the construction of emergent articulations such as the ones I am exploring. Merely writing a history of the present will not be productive unless its critique can somehow be articulated into the very processes of emergence that historians or anthropologists seek to examine.

Entities:  

Keywords:  Chinese medicine; bioscience; boundary objects; genealogy; medical humanities; systems biology; trading zones

Year:  2014        PMID: 25821530      PMCID: PMC4374107          DOI: 10.1215/18752160-2407180

Source DB:  PubMed          Journal:  East Asian Sci Technol Soc        ISSN: 1875-2152


  22 in total

1.  Traditional Kampo medicine: Unauthenticated in the Meiji era.

Authors:  Shigeo Sugiyama
Journal:  Hist Sci (Tokyo)       Date:  2004-03

Review 2.  Omics and its potential impact on R&D and regulation of complex herbal products.

Authors:  Olavi Pelkonen; Markku Pasanen; John C Lindon; Kelvin Chan; Liping Zhao; Greer Deal; Qihe Xu; Tai-Ping Fan
Journal:  J Ethnopharmacol       Date:  2012-02-01       Impact factor: 4.360

Review 3.  Potential role of metabolomic approaches for Chinese medicine syndromes and herbal medicine.

Authors:  Hui Sun; Aihua Zhang; Xijun Wang
Journal:  Phytother Res       Date:  2012-03-15       Impact factor: 5.878

4.  Chinese medicine in action: on the postcoloniality of medical practice in China.

Authors:  Eric I Karchmer
Journal:  Med Anthropol       Date:  2010-07

5.  Bridging the gap between traditional Chinese medicine and systems biology: the connection of Cold Syndrome and NEI network.

Authors:  Tao Ma; Conge Tan; Hui Zhang; Miqu Wang; Weijun Ding; Shao Li
Journal:  Mol Biosyst       Date:  2010-01-07

6.  The path to personalized medicine.

Authors:  Margaret A Hamburg; Francis S Collins
Journal:  N Engl J Med       Date:  2010-06-15       Impact factor: 91.245

Review 7.  Multi-target therapeutics: when the whole is greater than the sum of the parts.

Authors:  Grant R Zimmermann; Joseph Lehár; Curtis T Keith
Journal:  Drug Discov Today       Date:  2006-11-28       Impact factor: 7.851

Review 8.  Metabolomics in the context of systems biology: bridging traditional Chinese medicine and molecular pharmacology.

Authors:  Mei Wang; Robert-Jan A N Lamers; Henrie A A J Korthout; Joop H J van Nesselrooij; Renger F Witkamp; Rob van der Heijden; Peter J Voshol; Louis M Havekes; Rob Verpoorte; Jan van der Greef
Journal:  Phytother Res       Date:  2005-03       Impact factor: 5.878

9.  Systems biology guided by Chinese medicine reveals new markers for sub-typing rheumatoid arthritis patients.

Authors:  Herman van Wietmarschen; Kailong Yuan; Cheng Lu; Peng Gao; Jiangshan Wang; Cheng Xiao; Xiaoping Yan; Mei Wang; Jan Schroën; Aiping Lu; Guowang Xu; Jan van der Greef
Journal:  J Clin Rheumatol       Date:  2009-10       Impact factor: 3.517

10.  Calculating life? Duelling discourses in interdisciplinary systems biology.

Authors:  Jane Calvert; Joan H Fujimura
Journal:  Stud Hist Philos Biol Biomed Sci       Date:  2011-02-05
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  5 in total

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Authors:  Leslie de Vries
Journal:  Asian Med (Leiden)       Date:  2015

2.  Collectors, Producers, and Circulators of Tibetan and Chinese Medicines in Sichuan Province.

Authors:  Lena Springer
Journal:  Asian Med (Leiden)       Date:  2015

3.  A qualitative study of classical Chinese medicine in community health focusing on self-care: practitioner and staff perspectives.

Authors:  Alaia Harvie; Amie Steel; Jon Wardle
Journal:  Integr Med Res       Date:  2020-01-16

4.  The Case of the Suzhou Hospital of National Medicine (1939-41): War, Medicine, and Eastern Civilization.

Authors:  Keiko Daidoji; Eric I Karchmer
Journal:  East Asian Sci Technol Soc       Date:  2016-10-25

5.  Thinking differently with Chinese medicine: 'Explanations' and case studies for a postcolonial STS.

Authors:  Wen-Yuan Lin; John Law
Journal:  Soc Stud Sci       Date:  2022-05-21       Impact factor: 2.781

  5 in total

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