Literature DB >> 25821058

HUIEC, Human intestinal epithelial cell line with differentiated properties: process of isolation and characterisation.

Lidija Gradisnik1, Martin Trapecar1, Marjan Slak Rupnik2, Tomaz Velnar3,4.   

Abstract

The intestinal epithelium is composed of diverse cell types, most abundant being the enterocytes. Among other functions, they maintain the intestinal barrier and play a critical role in the absorption of nutrients, drugs and toxins. This study describes the development and characterization of human intestinal epithelial cells (HUIEC), a spontaneously arising cell line established by selective trypsinization and cloning of the intestinal epithelium, resulting in a uniform population of highly epithelial cells with a strong growth potential.

Entities:  

Keywords:  Cell isolation; Cell line; Cell model; Intestinal epithelial cells; Intestinal epithelium

Mesh：

Year:  2015        PMID： 25821058     DOI： 10.1007/s00508-015-0771-1

Source DB:  PubMed          Journal:  Wien Klin Wochenschr        ISSN： 0043-5325            Impact factor:   1.704


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