Ian J Koszewski 1 , Matthew R Hoffman 1 , W Greg Young 1 , Ying-Ta Lai 1 , Seth H Dailey 2 Show Affiliations »
Abstract
OBJECTIVE: To evaluate the safety, tolerability, and voice outcomes of office-based photoangiolytic laser treatment of Reinke's edema. STUDY DESIGN: Case series with chart review. SETTING: Academic medical center. SUBJECTS AND METHODS: We performed a retrospective analysis of patients undergoing office-based laser treatment of endoscopy-proven Reinke's edema. Safety and tolerability were evaluated by reviewing complications. Voice outcomes were analyzed by comparing pre- and postprocedural acoustic, aerodynamic, and Voice Handicap Index measurements. Complete data sets were not available for all subjects; sample size for each parameter is reported with the corresponding result. RESULTS: Nineteen patients met inclusion criteria. There were no minor or major complications. Five procedures were truncated due to patient intolerance. Phonatory frequency range increased (n = 12, P = .003), while percent jitter decreased (n = 12, P = .004). Phonation threshold pressure decreased after treatment (n = 4, P = .049). Voice Handicap Index also decreased (n = 14, P < .001). CONCLUSION: This study represents the largest series of patients undergoing office-based photoangiolytic laser treatment specifically for Reinke's edema. Our data suggest that this is a safe and effective modality to treat dysphonia associated with Reinke's edema, although patient intolerance of the procedure may represent a barrier. © American Academy of Otolaryngology—Head and Neck Surgery Foundation 2015.
OBJECTIVE: To evaluate the safety, tolerability, and voice outcomes of office-based photoangiolytic laser treatment of Reinke's edema . STUDY DESIGN: Case series with chart review. SETTING: Academic medical center. SUBJECTS AND METHODS: We performed a retrospective analysis of patients undergoing office-based laser treatment of endoscopy-proven Reinke's edema . Safety and tolerability were evaluated by reviewing complications. Voice outcomes were analyzed by comparing pre- and postprocedural acoustic, aerodynamic, and Voice Handicap Index measurements. Complete data sets were not available for all subjects; sample size for each parameter is reported with the corresponding result. RESULTS: Nineteen patients met inclusion criteria. There were no minor or major complications. Five procedures were truncated due to patient intolerance. Phonatory frequency range increased (n = 12, P = .003), while percent jitter decreased (n = 12, P = .004). Phonation threshold pressure decreased after treatment (n = 4, P = .049). Voice Handicap Index also decreased (n = 14, P < .001). CONCLUSION: This study represents the largest series of patients undergoing office-based photoangiolytic laser treatment specifically for Reinke's edema . Our data suggest that this is a safe and effective modality to treat dysphonia associated with Reinke's edema , although patient intolerance of the procedure may represent a barrier. © American Academy of Otolaryngology—Head and Neck Surgery Foundation 2015.
Entities: Disease
Species
Keywords:
Reinke’s edema; office-based treatment; photoangiolytic laser; voice
Mesh： See more »
Year: 2015
PMID： 25820581 DOI： 10.1177/0194599815577104
Source DB: PubMed Journal: Otolaryngol Head Neck Surg ISSN： 0194-5998 Impact factor: 3.497