Literature DB >> 25820293

Milk of calcium stones: radiological signs and management outcome.

M El-Shazly1.   

Abstract

Milk of calcium (MOC) is a rare type of stone that was first described in 1940 by Ludin and Howald who reported MOC in renal cysts. Milk of calcium is a viscous colloidal suspension of calcium salts. Stasis, obstruction and infection are important predisposing factors. Due to a layering effect, characteristic radiological signs especially in CT can help in diagnosis to avoid unsuccessful shock wave lithotripsy. This is the largest reported case series, in which radiological signs by CT scan to predict renal MOC stones, clinical picture and management outcome are described in detail. Cases with suspected renal milk of calcium stones were studied over 7 years (2008-2015). All cases were diagnosed preoperatively by non-contrast CT. Urine cultures were performed in all patients preoperatively. Intra-operative and postoperative findings were reported. Stones retrieved were sent for chemical analysis using an infrared method. Seven cases of milk of calcium renal stones were included in this study. These stones were faint radio-opaque in two cases and radiolucent in five cases. All cases were diagnosed preoperatively with non-contrast CT. Their Hounsfield units (HU) ranged from 114 to 612. All stones were located in a dependent position (gravitational effect) in the posterior aspect of dilated calyces. Five cases exhibited the typical fluid level and two cases demonstrated semilunar (half moon) pattern in the anterior surface of the stones. All cases underwent PCNL with suction and retrieval of soft stones without the need for disintegration. When stones demonstrate a low Hounsfield unit, are arranged in dependent positions within dilated calyces and exhibit fluid level or semilunar pattern on non-contrast CT, milk of calcium stones should be considered. PCNL is an effective modality for management of renal milk of calcium stones.

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Year:  2015        PMID: 25820293     DOI: 10.1007/s00240-015-0767-3

Source DB:  PubMed          Journal:  Urolithiasis        ISSN: 2194-7228            Impact factor:   3.436


  16 in total

Review 1.  Milk of calcium collection in the differential diagnosis of giant renal calculus.

Authors:  S Ulusan; Z Koc
Journal:  Br J Radiol       Date:  2008-02       Impact factor: 3.039

2.  Milk of calcium in the inferior calyx of a hydronephrotic kidney in a tetraplegic patient - a diagnosis to be made before scheduling for extracorporeal shock wave lithotripsy.

Authors:  S Vaidyanathan; R Parry; K F Parsons; G Singh; B M Soni; P Sett
Journal:  Spinal Cord       Date:  2000-05       Impact factor: 2.772

3.  Bilateral milk-of-calcium urine and hydronephrosis.

Authors:  S J McCorkell; T R Hefty; A D Dowling
Journal:  J Urol       Date:  1985-01       Impact factor: 7.450

Review 4.  Renal milk of calcium: review of the literature and report of 5 cases.

Authors:  C S Biyani; V Bhatia
Journal:  Urol Int       Date:  1993       Impact factor: 2.089

5.  Pyelocaliceal diverticula.

Authors:  M A Wulfsohn
Journal:  J Urol       Date:  1980-01       Impact factor: 7.450

6.  Atypical findings in a patient with a renal milky stone including a cake of stone.

Authors:  Tatsuya Uesugi; Takaharu Ichikawa
Journal:  Int J Urol       Date:  2006-08       Impact factor: 3.369

7.  [Imposing "calcium milk" lithiasis in giant hydronephrosis].

Authors:  P Bacchin; G Gasparini; G Paoli; F Di Tonno
Journal:  Minerva Urol Nefrol       Date:  1994-06       Impact factor: 3.720

Review 8.  [Milk of calcium syndrome: a diagnosis to be made before the scheduling of lithotripsy. Consideration apropos of 6 cases].

Authors:  G A Ouegnin; G Tobelem; E Thomas; C Economou; J Thomas; G Arvis
Journal:  Ann Urol (Paris)       Date:  1990

9.  Milk of calcium (MOC) cysts masquerading as renal calculi - a trap for the unwary.

Authors:  Shahid Aziz Anwer Khan; Faisal Rauf Khan; Matthew Shawcross Fletcher; Jonathan Leonard Richenberg
Journal:  Cent European J Urol       Date:  2012-09-04

10.  Rapidly developing renal milk of calcium in a patient with myelomonocytic leukaemia.

Authors:  Anika Morjaria; Gowrie Balasubramaniam; Saman Perera; Mike K Almond
Journal:  JRSM Open       Date:  2014-06-09
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