Angela Salso1, Francesco De Leonardis1, Raffaella Lionetti2, Ilaria Lenci3, Mario Angelico3, Andrea Telese3, Leonardo Baiocchi4. 1. Hepatology Unit, Policlinico Tor Vergata, Rome, Italy; Interdepartmental Endoscopic Service, Policlinico Tor Vergata, Rome, Italy. 2. INMI L. Spallanzani Hospital, Rome, Italy. 3. Hepatology Unit, Policlinico Tor Vergata, Rome, Italy. 4. Hepatology Unit, Policlinico Tor Vergata, Rome, Italy; Interdepartmental Endoscopic Service, Policlinico Tor Vergata, Rome, Italy. Electronic address: baiocchi@uniroma2.it.
Abstract
BACKGROUND: Few data are available on tolerability and quality of standard bowel cleansing for colonoscopy in patients with chronic disease. AIM: We seek to evaluate the tolerability and results of lavage solution for colonoscopy in cirrhotic patients in comparison with controls. METHODS: Fifty-three cirrhotic and fifty-two normal subjects undergoing colonoscopy were prospectively enrolled in the study. Data regarding tolerability of lavage solution were harvested at the pre-procedure visit. Data on level of bowel cleansing and other endoscopic variables were recorded after the procedure. RESULTS: Rate of failure to complete the prescribed bowel preparation and incidence of side effects during its administration were similar between cirrhotic and normal subjects. Despite this, cirrhotic patients exhibited an insufficient level of bowel preparation with approximately half exhibiting bad colon cleansing level (49% versus 5% control, p<0.001). CONCLUSION: Alternative bowel cleansing protocols are needed for cirrhotic subjects to better match their colonoscopic screening needs.
BACKGROUND: Few data are available on tolerability and quality of standard bowel cleansing for colonoscopy in patients with chronic disease. AIM: We seek to evaluate the tolerability and results of lavage solution for colonoscopy in cirrhotic patients in comparison with controls. METHODS: Fifty-three cirrhotic and fifty-two normal subjects undergoing colonoscopy were prospectively enrolled in the study. Data regarding tolerability of lavage solution were harvested at the pre-procedure visit. Data on level of bowel cleansing and other endoscopic variables were recorded after the procedure. RESULTS: Rate of failure to complete the prescribed bowel preparation and incidence of side effects during its administration were similar between cirrhotic and normal subjects. Despite this, cirrhotic patients exhibited an insufficient level of bowel preparation with approximately half exhibiting bad colon cleansing level (49% versus 5% control, p<0.001). CONCLUSION: Alternative bowel cleansing protocols are needed for cirrhotic subjects to better match their colonoscopic screening needs.
Authors: Seung Yong Shin; Kyeong Seon Ga; In Young Kim; Yoo Mi Park; Da Hyun Jung; Jie-Hyun Kim; Young Hoon Youn; Hyojin Park; Jae Jun Park Journal: Sci Rep Date: 2019-12-23 Impact factor: 4.379