Literature DB >> 25819343

Bufadienolides and polyhydroxycholestane derivatives from Bufo bufo gargarizans.

Yan-Min Wang1, Zong-Yun Li, Jing-Jing Wang, Xi-Yan Wu, Hui-Min Gao, Zhi-Min Wang.   

Abstract

A new polyhydroxycholestane sulfate ester, 3α,12β,25,26-tetrahydroxy-7-oxo-5β-cholestane 26-O-sulfate (1), was isolated from dried skin of Bufo bufo gargarizans Cantor and its structure was elucidated on the basis of extensive 1D and 2D NMR as well as HR-ESI-MS analysis. A comparison of steroidal metabolite profiles, based on HPLC and LC-MS analyses, indicates that the chemical compositions of the various parts of toads, such as venom, skin and stratum corneum, are significantly different.

Entities:  

Keywords:  Bufo bufo gargarizans; bufadienolide; polyhydroxycholestane sulfate; toad skin; toad venom

Mesh:

Substances:

Year:  2015        PMID: 25819343     DOI: 10.1080/10286020.2014.995174

Source DB:  PubMed          Journal:  J Asian Nat Prod Res        ISSN: 1028-6020            Impact factor:   1.569


  2 in total

1.  Chemical Profiling of Xueshuan Xinmaining Tablet by HPLC and UPLC-ESI-Q-TOF/MS.

Authors:  Ya-Xin Han; Peng-Fei Wang; Meng Zhao; Liang-Mian Chen; Zhi-Min Wang; Xiao-Qian Liu; Hui-Min Gao; Mu-Xin Gong; Hui Li; Ji-Zhong Zhu; Chuan-Gui Liu
Journal:  Evid Based Complement Alternat Med       Date:  2018-10-21       Impact factor: 2.629

2.  Comparative transcriptomes of three different skin sites for the Asiatic toad (Bufo gargarizans).

Authors:  Yue Lan; Lewei He; Xue Dong; Ruixiang Tang; Wanyu Li; Jiao Wang; Lei Wang; Bisong Yue; Megan Price; Tao Guo; Zhenxin Fan
Journal:  PeerJ       Date:  2022-02-22       Impact factor: 2.984

  2 in total

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