Literature DB >> 2581912

Effects of pinealectomy on regional brain serotonin metabolism.

M Aldegunde, I Miguez, J Veira.   

Abstract

The influence of pinealectomy on serotonin cerebral metabolism was examined in male rats maintained in a long photoperiod (14 h L:10 h D). Eight weeks after pinealectomy, serum, hepatic and CNS concentrations of tryptophan were not affected. The concentrations of 5-HT was significantly decreased in only three regions, hypothalamus, midbrain and hippocampus. The levels of 5-HIAA decreased significantly only in the hypothalamus and the midbrain. These results suggest that pinealectomy promotes a decreased hypothalamic and midbrain 5-HT utilization.

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Year:  1985        PMID： 2581912     DOI： 10.3109/00207458508985598

Source DB:  PubMed          Journal:  Int J Neurosci        ISSN： 0020-7454            Impact factor:   2.292


  6 in total

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Authors:  G Rozas; P Rey; M V Rozados; E Rebolledo; M Aldegunde
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Journal:  Front Neurol       Date:  2022-09-28       Impact factor: 4.086

5.  Pilot investigation of the circadian plasma melatonin rhythm across the menstrual cycle in a small group of women with premenstrual dysphoric disorder.

Authors:  Ari Shechter; Paul Lespérance; N M K Ng Ying Kin; Diane B Boivin
Journal:  PLoS One       Date:  2012-12-19       Impact factor: 3.240

6.  Effects of exogenous melatonin on sleep and circadian rhythms in women with premenstrual dysphoric disorder.

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  6 in total

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