Literature DB >> 25818242

Collection and laboratory methods for dried blood spots for hemoglobin A1c and total and high-density lipoprotein cholesterol in population-based surveys.

Ivey M Miller1, David A Lacher2, Te-Ching Chen2, George W Zipf2, Renee M Gindi3, Adena M Galinsky3, Tatiana Nwankwo2, Ana L Terry2.   

Abstract

BACKGROUND: The Health Measures at Home Study was a study designed to evaluate the feasibility of incorporating dried blood spots (DBS) collection into the National Health Interview Survey and to compare the proficiencies between field interviewers and health technicians in obtaining DBS.
METHODS: DBS collection and venipuncture were attempted on 125 participants. The DBS were collected in the participant's home and venous blood was collected in the National Health and Nutrition Examination Survey (NHANES) mobile examination center. The DBS results were compared to venous results in the NHANES for the measurements of hemoglobin A1c (HbA1c) and total and high-density lipoprotein (HDL) cholesterol.
RESULTS: Field interviewers and health technicians were able to collect the DBS for greater than 95% of participants. For DBS, health technicians and field interviewers were highly correlated for HbA1c (r=0.92) and total cholesterol (r=0.89), but not for HDL cholesterol (r=0.72). The DBS results of interviewers and health technicians compared to the venous method for HbA1c (r=0.90), but did not compare well for HDL cholesterol (r=0.64-0.66) and total cholesterol (r=0.65-0.67).
CONCLUSION: DBS was comparable to venous HbA1c, but not for total and HDL cholesterol. Health technicians and field interviewers had similar performance for DBS methods, except HDL cholesterol. Published by Elsevier B.V.

Entities:  

Keywords:  Diabetes; Dried blood spots; Laboratory method comparison; Lipids; Survey methods

Mesh:

Substances:

Year:  2015        PMID: 25818242      PMCID: PMC7442227          DOI: 10.1016/j.cca.2015.03.028

Source DB:  PubMed          Journal:  Clin Chim Acta        ISSN: 0009-8981            Impact factor:   3.786


  5 in total

Review 1.  What a drop can do: dried blood spots as a minimally invasive method for integrating biomarkers into population-based research.

Authors:  Thomas W McDade; Sharon Williams; J Josh Snodgrass
Journal:  Demography       Date:  2007-11

2.  Comparison of in-home collection of physical measurements and biospecimens with collection in a standardized setting: the health measures at home study.

Authors:  Renee M Gindi; George Zipf; Adena M Galinsky; Ivey M Miller; Tatiana Nwankwo; Ana L Terry
Journal:  Vital Health Stat 2       Date:  2014-04

3.  Million hearts: strategies to reduce the prevalence of leading cardiovascular disease risk factors--United States, 2011.

Authors: 
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4.  Comparison of dried blood spot to venous methods for hemoglobin A1c, glucose, total cholesterol, high-density lipoprotein cholesterol, and C-reactive protein.

Authors:  David A Lacher; Lewis E Berman; Te-Ching Chen; Kathryn S Porter
Journal:  Clin Chim Acta       Date:  2013-04-06       Impact factor: 3.786

5.  Comparability of HbA1c and lipids measured with dried blood spot versus venous samples: a systematic review and meta-analysis.

Authors:  Eshan T Affan; Devarsetty Praveen; Clara K Chow; Bruce C Neal
Journal:  BMC Clin Pathol       Date:  2014-05-12
  5 in total
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