Literature DB >> 25818230

Sesquiterpene coumarins from seeds of Ferula sinkiangensis.

Guangzhi Li1, Xiaojin Li2, Li Cao1, Lijing Zhang1, Liangang Shen1, Jun Zhu2, Junchi Wang1, Jianyong Si3.   

Abstract

A new sesquiterpene coumarin with a novel sesquiterpene carbon framework, Sinkiangenorin D, and ten known sesquiterpene coumarins were isolated from the seeds of Ferula sinkiangensis. The structures of these compounds, including the relative stereochemistry, were elucidated on the basis of spectroscopic data. All of the isolated compounds were tested against the AGS, HeLa, and K562 human cancer cell lines and showed cytotoxic activities with 50% inhibitory concentration values between 12.7 and 226.6 μM.
Copyright © 2015 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Colladonin (PubChem CID: 375430); Cytotoxic activities; Episamarcandin; Farnesiferl C (PubChem CID: 15559239); Feklone; Fekrynol; Ferula sinkiangensis; Feselol (PubChem CID: 17977); Lehmannolol; Lehmannolone; Sesquiterpene; Sesquiterpene coumarin; Sinkianone; Umbelliprenin (PubChem CID: 1781413)

Mesh：

Substances：

Year:  2015        PMID： 25818230     DOI： 10.1016/j.fitote.2015.03.022

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  9 in total

Review 1.  Coumarins in Food and Methods of Their Determination.

Authors:  Mirjana Lončar; Martina Jakovljević; Drago Šubarić; Martina Pavlić; Vlatka Buzjak Služek; Ines Cindrić; Maja Molnar
Journal:  Foods       Date:  2020-05-18

2.  Phytochemical screening and evaluation of the antimicrobial and antioxidant activities of Ferula caspica M. Bieb. extracts.

Authors:  Cigdem Kahraman; Gulacti Topcu; Erdal Bedir; I Irem Tatli; Melike Ekizoglu; Zeliha S Akdemir
Journal:  Saudi Pharm J       Date:  2019-02-02       Impact factor: 4.330

3.  Antioxidant, Anti-Inflammatory, and Antidiabetic Activities of Bioactive Compounds from the Fruits of Livistona chinensis Based on Network Pharmacology Prediction.

Authors:  Yuwei Wang; Jianxiu Zhai; Dan Yang; Na Han; Zhe Liu; Zhihui Liu; Sikai Li; Jun Yin
Journal:  Oxid Med Cell Longev       Date:  2021-10-18       Impact factor: 6.543

4.  Racemic Norlignans as Diastereoisomers from Ferula sinkiangensis Resins with Antitumor and Wound-Healing Promotion Activities.

Authors:  Ying-Shi Li; Bao-Chen Yang; Shu-Min Zheng; Yong-Xian Cheng; Hong-Hua Cui
Journal:  Molecules       Date:  2022-06-17       Impact factor: 4.927

5.  Umbelliprenin Increases the M1/M2 Ratio of Macrophage Polarization and Improves the M1 Macrophage Activity in THP-1 Cells Cocultured with AGS Cells.

Authors:  MohammadTaher Bahrami; Mostafa Haji Molla Hoseini; Mitra Rezaei; Seyed Ali Ziai
Journal:  Evid Based Complement Alternat Med       Date:  2021-07-13       Impact factor: 2.629

6.  Umbelliprenin induced both anti-inflammatory and regulatory cytokines in C57/BL6 mice.

Authors:  Narges Khaghanzadeh; Afshin Samiei; Zahra Mojtahedi; Mohammad Ramezani; Massood Hosseinzadeh; Abbas Ghaderi
Journal:  Iran J Basic Med Sci       Date:  2017-07       Impact factor: 2.699

7.  HPLC Analysis and Skin Whitening Effects of Umbelliprenin-containing Extracts of Anethum Graveolens, Pimpinella Anisum, and Ferulago Campestris.

Authors:  Vito Alessandro Taddeo; Francesco Epifano; Francesca Preziuso; Serena Fiorito; Nicolas Caron; Arnaud Rives; Philippe de Medina; Marc Poirot; Sandrine Silvente-Poirot; Salvatore Genovese
Journal:  Molecules       Date:  2019-01-30       Impact factor: 4.411

Review 8.  Recent Advances in the Synthesis of Coumarin Derivatives from Different Starting Materials.

Authors:  Melita Lončarić; Dajana Gašo-Sokač; Stela Jokić; Maja Molnar
Journal:  Biomolecules       Date:  2020-01-16

Review 9.  Cytotoxic activity of the genus Ferula (Apiaceae) and its bioactive constituents.

Authors:  Mehrdad Iranshahi; Ramin Rezaee; Mona Najaf Najafi; Ali Haghbin; Jamal Kasaian
Journal:  Avicenna J Phytomed       Date:  2018 Jul-Aug
  9 in total

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