| Literature DB >> 25817963 |
O Villena-Irigoyen1, L Echevarría-Lucas2, M Castro-Gómez3, R M Bellido-Muñoz3.
Abstract
CASE REPORT: The case is reported of acute retinal necrosis with bilateral involvement due to Varicella Zoster virus in a 77 year-old man. Polymerase chain reaction (PCR) of aqueous humor was positive for Varicella Zoster virus (VZV). He developed a Kyrieleis' vasculitis a month after the starting treatment, when the PCR analysis was negative. DISCUSSION: PCR is a quick and safe technique, with a high sensitivity and specificity of 97%, useful to diagnose and monitor the viral activity. The intervention must be urgent, due to the dramatically rapid evolution. Oral famciclovir oral is good alternative owing to its bioavailability.Entities:
Keywords: Acute retinal necrosis; Famciclovir; Kyrieleis’ vasculitis; Necrosis retiniana aguda; Necrotizing retinitis; Polymerase chain reaction; Reacción en cadena de la polimerasa; Retinal necrosis; Retinitis necrosantes; Vasculitis de Kyrieleis
Mesh:
Year: 2015 PMID: 25817963 DOI: 10.1016/j.oftal.2015.02.012
Source DB: PubMed Journal: Arch Soc Esp Oftalmol ISSN: 0365-6691