| Literature DB >> 25817238 |
Carla Julia da Silva Pessoa Vieira1, David José Ferreira da Silva1, Eriana Serpa Barreto1, Carlos Eduardo Hassegawa Siqueira2, Tatiana Elias Colombo3, Katia Ozanic3, Diane Johnson Schmidt4, Betânia Paiva Drumond5, Adriano Mondini6, Maurício Lacerda Nogueira3, Roberta Vieira de Morais Bronzoni7.
Abstract
Arboviruses are common agents of human febrile illness worldwide. In dengue-endemic areas illness due to other arboviruses have been misdiagnosed as dengue based only on clinical-epidemiological data. In this study we investigated the presence of Brazilian arboviruses in sera of 200 patients presenting acute febrile illness, during a dengue outbreak in Sinop, MT, Brazil. The results showed that 38 samples were positive to Dengue virus (DENV) type 1, two samples to DENV type 4, and six to Mayaro virus. These results indicate that arboviruses others than DENV are circulating in Sinop and the surrounding region, which are going undiagnosed. In addition, molecular and evolutionary analyses indicate that two MAYV genotypes are co-circulating in Mato Grosso, Brazil. Thus, a strong surveillance program must be implemented to evaluate and monitor the distribution and the true importance of non-dengue arboviruses in the etiology of acute febrile illnesses.Entities:
Keywords: Arboviruses; Febrile illness; RT-PCR
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Year: 2015 PMID： 25817238 DOI： 10.1016/j.actatropica.2015.03.020
Source DB: PubMed Journal: Acta Trop ISSN： 0001-706X Impact factor: 3.112