Literature DB >> 25817150

Tunneled buccal mucosa tube grafts for repair of proximal hypospadias.

Ronnie Fine1, Edward F Reda2, Paul Zelkovic3, Jordan Gitlin2, Jaime Freyle4, Israel Franco3, Lane S Palmer2.   

Abstract

PURPOSE: Buccal mucosa is the favored graft material for patients with long urethral defects and a paucity of skin. Since 2007, we have used the novel tunneled buccal mucosa tube graft urethroplasty technique in these patients. We describe this operative technique and report our surgical and functional outcomes.
MATERIALS AND METHODS: Between 2007 and 2013, 37 males with proximal hypospadias underwent tunneled buccal mucosa tube graft urethroplasty. After the penile shaft was optimized at a prior stage a free buccal graft was tubularized and tunneled under the intact ventral shaft skin and into the glans. We retrospectively reviewed all charts to report our results. We assessed uroflowmetry and bladder ultrasound for post-void residual urine.
RESULTS: The overall complications rate in 34 patients with more than 1-year followup was 32% (11), including fistula in 5, proximal stricture in 4 and meatal stenosis in 2. In the first 10 patients a total of 7 complications (70%) developed but there were only 4 complications in the next 24 (16%). Surgeon experience was the only significant predictor of complications (p = 0.003). We obtained uroflow and post-void residual urine data on 13 of 37 patients, of whom 9 achieved a normal flow pattern and post-void residual urine, and 4 had a blunted flow pattern.
CONCLUSIONS: The novel technique of the tunneled buccal mucosa tube graft in patients with proximal hypospadias represents a good alternative for a long urethroplasty in patients with a paucity of skin. After the learning curve plateaus the rate and degree of complications decrease. Furthermore, voiding function is adequate, as assessed by uroflow studies and post-void residual urine measurement.
Copyright © 2015 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  autografts; hypospadias; mouth mucosa; reconstructive surgical procedures; urethra

Mesh:

Year:  2015        PMID: 25817150     DOI: 10.1016/j.juro.2014.10.093

Source DB:  PubMed          Journal:  J Urol        ISSN: 0022-5347            Impact factor:   7.450


  3 in total

Review 1.  Proximal hypospadias: we aren't always keeping our promises.

Authors:  Christopher J Long; Douglas A Canning
Journal:  F1000Res       Date:  2016-09-26

2.  Urethral reconstruction with autologous urine-derived stem cells seeded in three-dimensional porous small intestinal submucosa in a rabbit model.

Authors:  Yang Liu; Wenjun Ma; Bo Liu; Yangcai Wang; Jiaqiang Chu; Geng Xiong; Lianju Shen; Chunlan Long; Tao Lin; Dawei He; Denis Butnaru; Lyundup Alexey; Yuanyuan Zhang; Deying Zhang; Guanghui Wei
Journal:  Stem Cell Res Ther       Date:  2017-03-09       Impact factor: 6.832

3.  Buccal Mucosal Grafts as a Novel Treatment for the Repair of Rectovaginal Fistulas: Protocol for an Upcoming Prospective Single-Surgeon Case Series.

Authors:  Caitlin Cahill; Natalia Kruger; John Heine
Journal:  JMIR Res Protoc       Date:  2022-04-29
  3 in total

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