Literature DB >> 25816997

Structure elucidation of the capsular polysaccharide of Acinetobacter baumannii AB5075 having the KL25 capsule biosynthesis locus.

Sof'ya N Senchenkova1, Alexander S Shashkov1, Anastasiya V Popova2, Mikhail M Shneider3, Nikolay P Arbatsky1, Konstantin A Miroshnikov3, Nikolay V Volozhantsev2, Yuriy A Knirel4.   

Abstract

Capsular polysaccharide was isolated by the phenol-water extraction of Acinetobacter baumannii AB5075 and studied by 1D and 2D (1)H and (13)C NMR spectroscopy. The following structure of the linear trisaccharide repeating unit was established: → 3)-β-D-ManpNAcA-(1 → 4)-β-D-ManpNAcA-(1 → 3)-α-D-QuipNAc4NR-(1 → where R indicates (S)-3-hydroxybutanoyl or acetyl in the ratio ∼ 2.5:1. The genes in the polysaccharide biosynthesis locus designated KL25 are appropriate to the established CPS structure.
Copyright © 2015 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Acinetobacter baumannii; Capsular polysaccharide structure; Polysaccharide gene locus

Mesh:

Substances:

Year:  2015        PMID: 25816997     DOI: 10.1016/j.carres.2015.02.011

Source DB:  PubMed          Journal:  Carbohydr Res        ISSN: 0008-6215            Impact factor:   2.104


  12 in total

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10.  Identification of Acinetobacter baumannii loci for capsular polysaccharide (KL) and lipooligosaccharide outer core (OCL) synthesis in genome assemblies using curated reference databases compatible with Kaptive.

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