| Literature DB >> 25816883 |
Omid Mashinchian1, Lesley-Anne Turner, Matthew J Dalby, Sophie Laurent, Mohammad Ali Shokrgozar, Shahin Bonakdar, Mohammad Imani, Morteza Mahmoudi.
Abstract
Stem cells are increasingly studied because of their potential to underpin a range of novel therapies, including regenerative strategies, cell type-specific therapy and tissue repair, among others. Bionanomaterials can mimic the stem cell environment and modulate stem cell differentiation and proliferation. New advances in these fields are presented in this review. This work highlights the importance of topography and elasticity of the nano-/micro-environment, or niche, for the initiation and induction of stem cell differentiation and proliferation.Keywords: biomimicking; differentiation; nanotechnology; niche; stem cells; substrates
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Year: 2015 PMID: 25816883 DOI: 10.2217/nnm.14.225
Source DB: PubMed Journal: Nanomedicine (Lond) ISSN: 1743-5889 Impact factor: 5.307