Literature DB >> 2581664

Depolarizing prepotentials are Na+ dependent in CA1 pyramidal neurons.

B A Macvicar.   

Abstract

Slow depolarizing prepotentials are important in controlling the frequency of neuronal firing in CA1 pyramidal cells. The ionic basis for subthreshold depolarizing potentials was examined in these experiments. Depolarizing prepotentials were concluded to be due to an inward Na+ current because they were blocked by reducing extracellular Na+ and by extracellular application of tetrodotoxin (TTX), and they were unaffected by blockers of inward Ca2+ currents.

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Year:  1985        PMID： 2581664     DOI： 10.1016/0006-8993(85)91597-5

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  10 in total

1.  Cell-attached measurements of the firing threshold of rat hippocampal neurones.

Authors:  D Fricker; J A Verheugen; R Miles
Journal:  J Physiol       Date:  1999-06-15       Impact factor: 5.182

2.  Synaptically triggered action potentials begin as a depolarizing ramp in rat hippocampal neurones in vitro.

Authors:  G Y Hu; O Hvalby; J C Lacaille; B Piercey; T Ostberg; P Andersen
Journal:  J Physiol       Date:  1992       Impact factor: 5.182

3.  Thresholds of action potentials evoked by synapses on the dendrites of pyramidal cells in the rat hippocampus in vitro.

Authors:  P Anderson; J Storm; H V Wheal
Journal:  J Physiol       Date:  1987-02       Impact factor: 5.182

4.  Post-natal development of electrophysiological properties of rat cerebral cortical pyramidal neurones.

Authors:  D A McCormick; D A Prince
Journal:  J Physiol       Date:  1987-12       Impact factor: 5.182

5.  Somatic amplification of distally generated subthreshold EPSPs in rat hippocampal pyramidal neurones.

Authors:  M Andreasen; J D Lambert
Journal:  J Physiol       Date:  1999-08-15       Impact factor: 5.182

6.  Cholinergic-dependent plateau potential in hippocampal CA1 pyramidal neurons.

Authors:  D D Fraser; B A MacVicar
Journal:  J Neurosci       Date:  1996-07-01       Impact factor: 6.167

7.  Electrophysiological properties of rat CA1 pyramidal neurones in vitro modified by changes in extracellular bicarbonate.

Authors:  J Church; H McLennan
Journal:  J Physiol       Date:  1989-08       Impact factor: 5.182

8.  Glutamate-induced action potentials are preceded by regenerative prepotentials in rat hippocampal pyramidal cells in vitro.

Authors:  G Y Hu; O Hvalby
Journal:  Exp Brain Res       Date:  1992       Impact factor: 1.972

9.  Membrane potential oscillations in CA1 hippocampal pyramidal neurons in vitro: intrinsic rhythms and fluctuations entrained by sinusoidal injected current.

Authors:  A García-Muñoz; L C Barrio; W Buño
Journal:  Exp Brain Res       Date:  1993       Impact factor: 1.972

10.  Ionic basis of spike after-depolarization and burst generation in adult rat hippocampal CA1 pyramidal cells.

Authors:  R Azouz; M S Jensen; Y Yaari
Journal:  J Physiol       Date:  1996-04-01       Impact factor: 5.182
  10 in total

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