Literature DB >> 2581624

HeLa cells have histamine H1-receptors which mediate activation of the K+ conductance.

A Hazama, T Yada, Y Okada.   

Abstract

HeLa cells responded to exogenous histamine with a transient hyperpolarization due to increased membrane conductance to K+. After successive applications of histamine, the cell membrane became virtually unresponsive (desensitized). The responses were blocked by pyrilamine but not by cimetidine. Thus, it appears that HeLa cells have H1-receptors which mediate an increase in the K+ conductance.

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Year:  1985        PMID： 2581624     DOI： 10.1016/0167-4889(85)90183-1

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  15 in total

1.  Short-term desensitization of the histamine H1 receptor in human HeLa cells: involvement of protein kinase C dependent and independent pathways.

Authors:  M J Smit; S M Bloemers; R Leurs; L G Tertoolen; A Bast; S W de Laat; H Timmerman
Journal:  Br J Pharmacol       Date:  1992-10       Impact factor: 8.739

2.  Single-channel analysis of the potassium permeability in HeLa cancer cells: evidence for a calcium-activated potassium channel of small unitary conductance.

Authors:  R Sauvé; C Simoneau; R Monette; G Roy
Journal:  J Membr Biol       Date:  1986       Impact factor: 1.843

3.  Single calcium-activated potassium channel in cultured mammary epithelial cells.

Authors:  K Furuya; K Enomoto; S Furuya; S Yamagishi; C Edwards; T Oka
Journal:  Pflugers Arch       Date:  1989-06       Impact factor: 3.657

4.  Oscillatory activation of calcium-dependent potassium channels in HeLa cells induced by histamine H1 receptor stimulation: a single-channel study.

Authors:  R Sauvé; C Simoneau; L Parent; R Monette; G Roy
Journal:  J Membr Biol       Date:  1987       Impact factor: 1.843

5.  Ca2+ sensitivity of volume-regulatory K+ and Cl- channels in cultured human epithelial cells.

Authors:  A Hazama; Y Okada
Journal:  J Physiol       Date:  1988-08       Impact factor: 5.182

6.  Histamine-H1-receptor-mediated phosphoinositide hydrolysis, Ca2+ signalling and membrane-potential oscillations in human HeLa carcinoma cells.

Authors:  B C Tilly; L G Tertoolen; A C Lambrechts; R Remorie; S W de Laat; W H Moolenaar
Journal:  Biochem J       Date:  1990-02-15       Impact factor: 3.857

7.  Characterisation of Ca(2+)-dependent inwardly rectifying K+ currents in HeLa cells.

Authors:  M Díaz; F V Sepúlveda
Journal:  Pflugers Arch       Date:  1995-06       Impact factor: 3.657

8.  Internalization of Shigella flexneri into HeLa cells occurs without an increase in cytosolic Ca2+ concentration.

Authors:  P L Clerc; B Berthon; M Claret; P J Sansonetti
Journal:  Infect Immun       Date:  1989-09       Impact factor: 3.441

9.  Desensitization of histamine H1 receptor-mediated inositol phosphate production in HeLa cells.

Authors:  D R Bristow; M R Zamani
Journal:  Br J Pharmacol       Date:  1993-06       Impact factor: 8.739

10.  Regulation of Ca2+ influx during mitosis: Ca2+ influx and depletion of intracellular Ca2+ stores are coupled in interphase but not mitosis.

Authors:  S F Preston; R I Sha'afi; R D Berlin
Journal:  Cell Regul       Date:  1991-11
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