Literature DB >> 2581463

Inhibitory effect of cyclosporin A on histamine release from human leukocytes and rat mast cells.

C Pedersen, H Permin, P Stahl Skov, S Norn, M Svenson, H Mosbech, K Bendtzen.   

Abstract

The influence of cyclosporin A (CyA) on human basophil histamine release induced in vitro by specific antigen, anti-IgE, calcium ionophore A23187, or concanavalin A (Con A) was studied. CyA inhibited the release induced by these four stimulators. It is suggested that the drug acts directly on the target cell, since similar effect was obtained with isolated peritoneal rat mast cells. The basophil histamine release was not changed by a non-immunosuppressive cyclosporin derivate.

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Year:  1985        PMID： 2581463     DOI： 10.1111/j.1398-9995.1985.tb02668.x

Source DB:  PubMed          Journal:  Allergy        ISSN： 0105-4538            Impact factor:   13.146


  9 in total

1.  Opioids from immunocytes interact with receptors on sensory nerves to inhibit nociception in inflammation.

Authors:  C Stein; A H Hassan; R Przewłocki; C Gramsch; K Peter; A Herz
Journal:  Proc Natl Acad Sci U S A       Date:  1990-08       Impact factor: 11.205

2.  Effect of cyclosporin-A on histamine release from tracheal strips of sensitized guinea pigs.

Authors:  M Bovingdon; E S Assem; B Y Wan
Journal:  Inflamm Res       Date:  1996-03       Impact factor: 4.575

3.  Lack of inhibition by cyclosporin in the Schultz-Dale reaction.

Authors:  E S Assem; C I Ezeamuzie; B Y Wan; Y Ayalew
Journal:  Inflamm Res       Date:  1995-04       Impact factor: 4.575

4.  Inhibition of histamine release from human lung and rat peritoneal mast cells by cyclosporin-A.

Authors:  I C Ezeamuzie; E S Assem
Journal:  Agents Actions       Date:  1990-04

5.  Effects of cyclosporin A and FK506 on Fc epsilon receptor type I-initiated increases in cytokine mRNA in mouse bone marrow-derived progenitor mast cells: resistance to FK506 is associated with a deficiency in FK506-binding protein FKBP12.

Authors:  R E Kaye; D A Fruman; B E Bierer; M W Albers; L D Zydowsky; S I Ho; Y J Jin; M C Castells; S L Schreiber; C T Walsh
Journal:  Proc Natl Acad Sci U S A       Date:  1992-09-15       Impact factor: 11.205

6.  Effect of cyclosporin A on rat mucosal mast cells and the associated protease RMCPII.

Authors:  A G Cummins; G H Munro; A Ferguson
Journal:  Clin Exp Immunol       Date:  1988-04       Impact factor: 4.330

7.  Selective early production of CCL20, or macrophage inflammatory protein 3alpha, by human mast cells in response to Pseudomonas aeruginosa.

Authors:  Tong-Jun Lin; Lauren H Maher; Kaede Gomi; Jeffrey D McCurdy; Rafael Garduno; Jean S Marshall
Journal:  Infect Immun       Date:  2003-01       Impact factor: 3.441

8.  Effects of cyclosporin A on humoral immunity to ticks and on cutaneous immediate and delayed hypersensitivity reactions to Ixodes ricinus L. salivary-gland antigens in re-infested rabbits.

Authors:  P Girardin; M Brossard
Journal:  Parasitol Res       Date:  1989       Impact factor: 2.289

9.  NFAT but not NF-kappaB is critical for transcriptional induction of the prosurvival gene A1 after IgE receptor activation in mast cells.

Authors:  Erik Ullerås; Mats Karlberg; Christine Möller Westerberg; Jessica Alfredsson; Steve Gerondakis; Andreas Strasser; Gunnar Nilsson
Journal:  Blood       Date:  2008-01-08       Impact factor: 22.113
  9 in total

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