Literature DB >> 25814306

Transcriptional mimicry by tumor-associated stroma.

Hoon Kim1, Roel G W Verhaak2.   

Abstract

Recent molecular classification of colorectal cancer (CRC) has identified a poor-prognosis transcriptional subtype associated with mesenchymal traits. New studies used CRC transcriptomic data to show that tumor-associated stroma mimics the gene signature of epithelial-to-mesenchymal transition (EMT) and found no evidence for EMT of colorectal tumor cells.

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Year:  2015        PMID： 25814306     DOI： 10.1038/ng.3255

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


  9 in total

Review 1.  Developmental origins and oncogenic pathways in malignant brain tumors.

Authors:  Q Richard Lu; Lily Qian; Xianyao Zhou
Journal:  Wiley Interdiscip Rev Dev Biol       Date:  2019-04-03       Impact factor: 5.814

Review 2.  Harnessing OLIG2 function in tumorigenicity and plasticity to target malignant gliomas.

Authors:  Jennifer Kosty; Fanghui Lu; Robert Kupp; Shwetal Mehta; Q Richard Lu
Journal:  Cell Cycle       Date:  2017-08-14       Impact factor: 4.534

3.  Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment.

Authors:  Qianghu Wang; Baoli Hu; Xin Hu; Hoon Kim; Massimo Squatrito; Lisa Scarpace; Ana C deCarvalho; Sali Lyu; Pengping Li; Yan Li; Floris Barthel; Hee Jin Cho; Yu-Hsi Lin; Nikunj Satani; Emmanuel Martinez-Ledesma; Siyuan Zheng; Edward Chang; Charles-Etienne Gabriel Sauvé; Adriana Olar; Zheng D Lan; Gaetano Finocchiaro; Joanna J Phillips; Mitchel S Berger; Konrad R Gabrusiewicz; Guocan Wang; Eskil Eskilsson; Jian Hu; Tom Mikkelsen; Ronald A DePinho; Florian Muller; Amy B Heimberger; Erik P Sulman; Do-Hyun Nam; Roel G W Verhaak
Journal:  Cancer Cell       Date:  2017-07-10       Impact factor: 31.743

4.  Novel MET/TIE2/VEGFR2 inhibitor altiratinib inhibits tumor growth and invasiveness in bevacizumab-resistant glioblastoma mouse models.

Authors:  Yuji Piao; Soon Young Park; Verlene Henry; Bryan D Smith; Ningyi Tiao; Daniel L Flynn; John F de Groot
Journal:  Neuro Oncol       Date:  2016-03-09       Impact factor: 12.300

5.  ROCK2 inhibition triggers the collective invasion of colorectal adenocarcinomas.

Authors:  Fotine Libanje; Joel Raingeaud; Rui Luan; ZoéAp Thomas; Olivier Zajac; Joel Veiga; Laetitia Marisa; Julien Adam; Valerie Boige; David Malka; Diane Goéré; Alan Hall; Jean-Yves Soazec; Friedrich Prall; Maximiliano Gelli; Peggy Dartigues; Fanny Jaulin
Journal:  EMBO J       Date:  2019-06-18       Impact factor: 11.598

6.  Exosomal miR-30a and miR-222 derived from colon cancer mesenchymal stem cells promote the tumorigenicity of colon cancer through targeting MIA3.

Authors:  Qiong Du; Xuan Ye; Sheng-Rong Lu; Huan Li; Hong-Yue Liu; Qing Zhai; Bo Yu
Journal:  J Gastrointest Oncol       Date:  2021-02

7.  AIF inhibits tumor metastasis by protecting PTEN from oxidation.

Authors:  Shao-Ming Shen; Meng Guo; Zhong Xiong; Yun Yu; Xu-Yun Zhao; Fei-Fei Zhang; Guo-Qiang Chen
Journal:  EMBO Rep       Date:  2015-09-28       Impact factor: 8.807

Review 8.  Cilia in autophagy and cancer.

Authors:  Muqing Cao; Qing Zhong
Journal:  Cilia       Date:  2016-02-03

Review 9.  Longitudinal Characteristics of Glioblastoma in Genome-Wide Studies.

Authors:  Zoltan Kraboth; Bernadette Kalman
Journal:  Pathol Oncol Res       Date:  2019-08-03       Impact factor: 3.201
  9 in total

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