Literature DB >> 25814026

Successful emergency splenectomy during cardiac arrest due to cytomegalovirus-induced atraumatic splenic rupture.

Matilde Kanstrup Glesner1, Kristian Roerbaek Madsen2, Jesper Meng Rahn Nielsen3, Stefan Posth4.   

Abstract

A 27-year-old woman was admitted to the emergency department with fever and a petechial rash on suspicion of meningitis. Shortly after arriving she developed cardiac arrest. Blood work up showed severe lactate acidosis, anaemia and thrombocytopenia. A focused assessment with sonography in trauma scan showed free intraperitoneal fluid and an emergency laparotomy revealed massive bleeding from a ruptured spleen. The patient was successfully resuscitated. She proved to be infected with cytomegalovirus causing idiopathic thrombocytopenic purpura, splenomegaly and splenic rupture. She was treated for 14 days with ganciclovir and meropenem and discharged on recovery. Atraumatic splenic rupture caused by viral infection is a rare condition although well described. In the case of our patient, thrombocytopenia added to the severity of the splenic rupture. A multidisciplinary team approach was essential for the management and the eventual recovery of the patient. 2015 BMJ Publishing Group Ltd.

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Year:  2015        PMID: 25814026      PMCID: PMC4386418          DOI: 10.1136/bcr-2014-208094

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  3 in total

1.  Cytomegalovirus can make immune thrombocytopenic purpura refractory.

Authors:  Dina DiMaggio; Alan Anderson; James B Bussel
Journal:  Br J Haematol       Date:  2009-05-09       Impact factor: 6.998

Review 2.  Systematic review of atraumatic splenic rupture.

Authors:  P Renzulli; A Hostettler; A M Schoepfer; B Gloor; D Candinas
Journal:  Br J Surg       Date:  2009-10       Impact factor: 6.939

Review 3.  613 cases of splenic rupture without risk factors or previously diagnosed disease: a systematic review.

Authors:  F Kris Aubrey-Bassler; Nicholas Sowers
Journal:  BMC Emerg Med       Date:  2012-08-14
  3 in total

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