| Literature DB >> 25812207 |
M M Abdellatif, A A Ibrahim, A I Khalafalla.
Abstract
A strain of camelpox virus (CMLV) isolated in the Sudan was attenuated by serial passage in Vero cell monolayers for use as a future vaccine strain. The safety and potency of passage 115 virus (designated Sudan CMLV/115) was tested. Camels inoculated with CMLV/115 showed no clinical disease or skin lesions, developed low-level antibodies and cell-mediated immune response and resisted challenge with virulent wild-type CMLV. Field testing of the candidate vaccine showed that the developed vaccine induces immune response and is safe for young and pregnant camels.Entities:
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Year: 2014 PMID： 25812207 DOI： 10.20506/rst.33.3.2321
Source DB: PubMed Journal: Rev Sci Tech ISSN： 0253-1933 Impact factor: 1.181